June 25, 2015
June 25, 2015 —
UC San Diego School of Medicine researchers report that the amyloid cascade hypothesis, long believed to describe the pathology of Alzheimer’s disease, is not a fixed and invariable sequence of events. Rather, early indicators or biomarkers of the neurodegenerative condition vary by individual, making preclinical diagnoses more challenging.
June 24, 2015
June 24, 2015 —
Leading computational biologist Jill P. Mesirov, PhD, has been appointed associate vice chancellor for computational health sciences and professor of medicine at University of California, San Diego School of Medicine and Moores Cancer Center. Mesirov most recently served as associate director and chief informatics officer at the Broad Institute of MIT and Harvard, where she directed the Computational Biology and Bioinformatics Program.
June 19, 2015
June 19, 2015 —
Psychiatric disorders can be difficult to diagnose because clinicians must rely upon interpreted clues, such as a patient’s behaviors and feelings. For the first time, researchers at University of California, San Diego School of Medicine report identifying a biological marker: the over-production of specific genes that could be a diagnostic indicator of mental illness in female psychiatric patients.
June 18, 2015
June 18, 2015 —
Researchers at University of California, San Diego School of Medicine have made a surprisingly simple discovery: The modification of more than 100 secreted proteins is the work of a single enzyme called Fam20C. The finding is published June 18 by Cell.
June 17, 2015
June 17, 2015 —
Metastatic colorectal cancer patients tend to live longer when they respond to the first line of chemotherapy their doctors recommend. To better predict how patients will respond to chemotherapy drugs before they begin treatment, researchers at University of California, San Diego School of Medicine conducted a proof-of-principle study with a small group of metastatic colorectal cancer patients. The results revealed two genes that could help physicians make more informed treatment decisions for patients with this disease.
June 17, 2015
June 17, 2015 —
Higher consumption of dietary trans fatty acids (dTFA), commonly used in processed foods to improve taste, texture and durability, has been linked to worsened memory function in men 45 years old and younger, according to a University of California, San Diego School of Medicine study published online on June 17 in PLOS ONE.
June 10, 2015
June 10, 2015 —
Researchers at the University of California, San Diego School of Medicine have launched a clinical trial to investigate the safety and efficacy of an unprecedented drug therapy for autism.
June 8, 2015
June 8, 2015 —
Researchers at University of California, San Diego School of Medicine and University College Dublin (UCD) have found that augmenting a naturally occurring molecule in the body can help protect against obesity-related diseases by reducing inflammation in the fat tissues. The study, published June 4 in the journal Cell Metabolism, focused on liver and kidney diseases, but the researchers believe it could lead to a new therapeutic approach for a variety of obesity-fueled conditions.
June 1, 2015
June 1, 2015 —
People with achromatopsia, an inherited eye disorder, see the world literally in black and white. Worse yet, their extreme sensitivity to light makes them nearly blind in bright sunlight. Now, researchers at University of California, San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health System have identified a previously unknown gene mutation that underlies this disorder.
May 31, 2015
May 31, 2015 —
Accurately assessing pain in children in a clinical setting can be difficult. A study by researchers at the University of California, San Diego School of Medicine has demonstrated the validity of a new method for measuring pediatric pain levels using novel facial pattern recognition software.
