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News Archive - School of Medicine

SDSC Receives 2015 HPCwire Editors’ Choice Award for ‘Comet’ Supercomputer

November 17, 2015

The San Diego Supercomputer Center at the University of California, San Diego, is a recipient of this year’s HPCwire and Editors’ Choice Awards for its new Comet supercomputer that entered production earlier this year as a result of a National Science Foundation grant worth nearly $24 million including hardware and operating funds.

RNA-Based Drugs Give More Control Over Gene Editing

November 16, 2015

In just the past few years, researchers have found a way to use a naturally occurring bacterial system known as CRISPR/Cas9 to inactivate or correct specific genes in any organism. CRISPR/Cas9 gene editing activity runs continuously, though, leading to risk of additional editing at unwanted sites. Now, researchers at University of California, San Diego School of Medicine, Ludwig Cancer Research and Isis Pharmaceuticals demonstrate a commercially feasible way to use RNA to turn the CRISPR-Cas9 system on and off as desired — permanently editing a gene, but only temporarily activating CRISPR-Cas9.

Renowned Surgeon Christopher J. Kane Named to Joseph D. Schmidt, MD Presidential Chair in Urology

November 16, 2015

Christopher J. Kane, M.D., a renowned specialist in prostate cancer and an expert in robotic and other minimally invasive procedures for urologic surgery at the University of California, San Diego, has been appointed the inaugural holder of the Joseph D. Schmidt, MD Presidential Chair in Urology in the School of Medicine.

New Technique Could Expand Number of Diseases Detected by Noninvasive Prenatal Testing

November 9, 2015

Researchers at the University of California, San Diego School of Medicine developed a method to expand the types of chromosomal abnormalities that noninvasive prenatal testing (NIPT) can detect. The study, published November 9 by Proceedings of the National Academy of Sciences, uses a semiconductor sequencing platform to identify small chromosomal deletions or duplications, such as occur in Cri du Chat Syndrome and DiGeorge Syndrome, with a simple blood test from the expectant mother.

UC San Diego Health Researchers Join Pancreatic Cancer “Dream Team”

November 9, 2015

In an effort to advance research on one of the deadliest forms of cancer, University of California, San Diego School of Medicine researchers Andrew Lowy, MD, and Tannishtha Reya, PhD, have been recruited for their expertise in preclinical modeling, clinical trials and stem cell biology to join a “dream team” of international pancreatic cancer researchers.

Healthy Aging Initiative at UC San Diego Announces Inaugural Research Projects

November 5, 2015

The Healthy Aging Initiative (HAI), a campus-wide effort to investigate and address the diverse challenges and needs of the nation’s aging population, has announced its inaugural research and education seed grants to seven University of California, San Diego faculty members

Cancer-associated Mutations are Common in Patients with Unexplained Low Blood Counts

November 3, 2015

Patients with unexplained low blood counts and abnormally mutated cells who do not fit the diagnostic criteria for recognized blood cancers should be described as having clonal cytopenias of undetermined significance, suggest UC San Diego School of Medicine researchers in a recent paper. The researchers found the condition surprisingly common in older patients with low blood counts.

Researchers are on Their Way to Predicting What Side Effects You’ll Experience From a Drug

November 2, 2015

Researchers at the University of California, San Diego have developed a model that could be used to predict a drug’s side effects on different patients. The proof of concept study is aimed at determining how different individuals will respond to a drug treatment and could help assess whether a drug is suitable for a particular patient based on measurements taken from the patient’s blood.

New Computational Strategy Finds Brain Tumor-Shrinking Molecules

October 30, 2015

Patients with glioblastoma, a type of malignant brain tumor, usually survive fewer than 15 months following diagnosis. Since there are no effective treatments for the deadly disease, University of California, San Diego researchers developed a new computational strategy to search for molecules that could be developed into glioblastoma drugs. In mouse models of human glioblastoma, one molecule they found shrank the average tumor size by half. The study is published October 30 by Oncotarget.

Bipolar Patients’ Brain Cells Predict Response to Lithium

October 30, 2015

The brain cells of patients with bipolar disorder, a manic-depressive illness characterized by severe swings in mood, energy and ability to carry out daily tasks, are more sensitive to stimuli than other people’s brain cells, reports an international team of scientists headed by researchers at Salk Institute for Biological Studies and University of California, San Diego School of Medicine.
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