September 20, 2018
September 20, 2018 —
Using a bioinformatics approach, University of California San Diego School of Medicine researchers found that CD4+ T cell’s binding partner, a molecule called MHC-II, may have even more influence on emerging tumors than MHC-I, the better known partner of CD8+ T cells. The finding, published September 20 in Cell, may help researchers improve cancer immunotherapies and predict which patients will respond best.
September 18, 2018
September 18, 2018 —
Researchers at University of California San Diego School of Medicine have unraveled new insights into the way cells leverage G-protein-coupled receptors (GPCRs) and their cellular waste disposal systems to control inflammation. The findings, published September 18 in Cell Reports, suggest some existing cancer drugs that inhibit these cellular activities might be repurposed to treat vascular inflammation, which occurs when artery-blocking plaques form in atherosclerosis.
September 18, 2018
September 18, 2018 —
Researchers at University of California School of Medicine are preparing to launch a novel clinical trial to examine the safety, efficacy and pharmacological properties of cannabis as a potential treatment for adults with essential tremor (ET). Currently, ET is treated using repurposed medications originally developed for high blood pressure or seizures.
September 17, 2018
September 17, 2018 —
On Saturday, October 6, hundreds of hackers are expected to descend upon the University of California San Diego campus to put their collaborative problem-solving capabilities to the test. The fast-paced, two-day event brings together interdisciplinary teams to identify and solve some of today’s most pressing health challenges, such as antibiotic resistance, opioid abuse and management of mental illness.
September 13, 2018
September 13, 2018 —
Researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego have now identified three new molecular drug targets in Naegleria fowleri and a number of drugs that are able to inhibit the amoeba’s growth in a laboratory dish. Several of these drugs are already approved by the U.S. Food and Drug Administration for other uses, such as antifungal agents, the breast cancer drug tamoxifen and antidepressant Prozac.
September 13, 2018
September 13, 2018 —
The Nikon Imaging Center, a collaborative microscopy center that provides local researchers with access to the latest imaging technologies, opened September today at the University of California San Diego.
September 13, 2018
September 13, 2018 —
Researchers at University of California San Diego School of Medicine have discovered using mice and human clinical specimens, that caspase-2, a protein-cleaving enzyme, is a critical driver of non-alcoholic steatohepatitis (NASH), a chronic and aggressive liver condition. By identifying caspase-2’s critical role, they believe an inhibitor of this enzyme could provide an effective way to stop the pathogenic progression that leads to NASH — and possibly even reverse early symptoms.
September 12, 2018
September 12, 2018 —
A new wearable ultrasound patch that non-invasively monitors blood pressure in arteries deep beneath the skin could help people detect cardiovascular problems earlier on and with greater precision. In tests, the patch performed as well as some clinical methods to measure blood pressure. Applications include real-time, continuous monitoring of blood pressure changes in patients with heart or lung disease, as well as patients who are critically ill or undergoing surgery.
September 12, 2018
September 12, 2018 —
Researchers at the University of California San Diego say they have dramatically advanced the science of biometric identification, creating a novel technology that can capture the fingerprints of infants and children, even on the first day of birth.
September 11, 2018
September 11, 2018 —
Two to three million years ago, the functional loss of a single gene triggered a series of changes in what would eventually become the modern human species. Researchers at University of California San Diego School of Medicine report on studies of mice engineered to lack the same gene and resulting data that suggest the lost gene may also have contributed to humanity’s well-documented claim to be among the best long-distance runners in the animal kingdom.
