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News Archive - School of Medicine

Exposure to Glyphosate, Chemical Found in Weed Killers, Increased Over 23 Years

October 24, 2017

Analyzing samples from a prospective study, University of California San Diego School of Medicine researchers found that human exposure to glyphosate, a chemical widely found in weed killers, has increased approximately 500 percent since the introduction of genetically modified crops.

The Microbial Anatomy of an Organ

October 19, 2017

University of California San Diego researchers have developed the first 3D spatial visualization tool for mapping “’omics” data onto whole organs. The tool helps researchers and clinicians understand the effects of chemicals, such as microbial metabolites and medications, on a diseased organ in the context of microbes that also inhabit the region. The work could advance targeted drug delivery for cystic fibrosis and other conditions where medications are unable to penetrate.

Inflamed Support Cells Appear to Contribute to Some Kinds of Autism

October 18, 2017

Modeling the interplay between neurons and astrocytes derived from children with Autism Spectrum Disorder (ASD), researchers at University of California San Diego School of Medicine, with colleagues in Brazil, say innate inflammation in the latter appears to contribute to neuronal dysfunction in at least some forms of the disease.

Germs Are Your Friends, Top UC San Diego Scientist Shares the Dirt

October 17, 2017

A noted scholar and a world-leader in microbiome research, Rob Knight, Ph.D. will take guests inside the human body and share the dirt on the microbiome, the focus of his new book, published in June 2017. On Tuesday, October 24, Knight will discuss Dirt Is Good: The Advantage of Germs for Your Child’s Developing Immune System, from 5:30 – 7:00 p.m. in Geisel Library’s Seuss Room. The UC San Diego Library talk is free to attend and open to the public. A reception and a book signing with Dr. Knight will follow. Copies of the book will be available for purchase at the event from the UC San Diego Bookstore.

Powered by Chemo: Patient with Advanced Pancreatic Cancer Tackles Ironman Triathlon

October 10, 2017

Despite a diagnosis of stage IV pancreatic cancer and ongoing chemotherapy, Mike Levine boarded a plane this past weekend destined for Kona, Hawaii, where he will compete in one of the most grueling of physical competitions: the Ironman World Championship. Cheering him on will be his wife Jan, friends and Paul Fanta, MD, a pancreatic cancer expert with Moores Cancer Center at UC San Diego Health who has been treating Levine since 2016.

Common Acid Reflux Medications Promote Chronic Liver Disease

October 10, 2017

Approximately 10 percent of Americans take a proton pump inhibitor drug to relieve symptoms of frequent heartburn and acid reflux. That percentage can be much higher for people with chronic liver disease. Researchers at University of California San Diego School of Medicine have discovered evidence in mice and humans that these medications alter gut bacteria in a way that promotes three types of chronic liver disease. The study is published October 10 in Nature Communications.

Gene Identified That May Provide Potential Therapy for Cerebral Cavernous Malformations

October 9, 2017

Researchers at University of California San Diego School of Medicine, with national collaborators, have identified a series of molecular clues to understanding the formation of cerebral cavernous malformations (CCMs). The study offers the first genome-wide analysis of the transcriptome of brain microvascular endothelial cells after KRIT1 inactivation.

Liquid Biopsy May Be New Way to Detect Liver Cancer Earlier, Easier

October 9, 2017

An international team of researchers at University of California San Diego School of Medicine and Moores Cancer Center, with colleagues at Sun Yet-sun University Cancer Center and other collaborating institutions, have developed a new diagnostic and prognosis method for early detection of hepatocellular carcinoma (HCC), based on a simple blood sample containing circulating tumor DNA.

New Technology Enables Shorter Radiation Treatment Time for Patients

October 3, 2017

Patients at UC San Diego Health in need of radiation therapy now have access to the next generation of radiation treatment technology. The new radiotherapy system significantly reduces treatment times with improved accuracy.

DNA Mutations Shed in Blood Predicts Response to Immunotherapy in Patients with Cancer

October 1, 2017

In a first-of-its-kind study, University of California San Diego School of Medicine researchers report that a blood sample, or liquid biopsy, can reveal which patients will respond to checkpoint inhibitor-based immunotherapies.
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