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News Archive - Scott Lafee

Untangling Tau: Researchers Find a “Druggable Target” for Treating Alzheimer’s Disease

January 24, 2019

Using induced pluripotent stem cell-derived neurons from Alzheimer’s patients, UC San Diego researchers say cholesteryl esters — the storage product for excess cholesterol within cells — act as regulators of the protein tau, providing a new druggable target for the disease.

Youthful Cognitive Ability Strongly Predicts Mental Capacity Later in Life

January 21, 2019

Early adult general cognitive ability is a stronger predictor of cognitive function and reserve later in life than other factors, such as higher education, occupational complexity or engaging in late-life intellectual activities.

3D Printed Implants Show Promise for Treating Spinal Cord Injury

January 17, 2019

3D printed implants could one day help restore neural connections and lost motor function in patients with spinal cord injury. The implants, developed by engineers and neuroscientists at the University of California San Diego, are soft bridges that guide new nerve cells to grow across the site at which the spinal cord has been severed. The work has so far shown promise in rats with severe spinal cord injury.

3D Printed Implant Promotes Nerve Cell Growth to Treat Spinal Cord Injury

January 14, 2019

For the first time, researchers at University of California San Diego have used rapid 3D printing technologies to create a spinal cord, then successfully implanted that scaffolding, loaded with neural stem cells, into sites of severe spinal cord injury in rats.

Maternal Programming During Pregnancy Induces Long-Term Postpartum Obesity

January 8, 2019

In a new study using a mouse model, researchers at University of California San Diego School of Medicine suggest that long-term postpartum weight gain may be due not so much to retained fat as to reprogramming of maternal energy metabolism.

With OK From FDA, UC San Diego Researchers Prepare to Launch Novel Phage Study

January 8, 2019

FDA approves first U.S. clinical trial of an intravenously administered bacteriophage-based therapy to treat resistant bacterial infections.

An Errant Editing Enzyme Promotes Tumor Suppressor Loss and Leukemia Propagation

January 3, 2019

UC San Diego researchers have found a stem cell enzyme copy edits more than 20 tumor types, providing new therapeutic target for preventing cancer cell resistance to chemotherapy and radiation.

Serious Loneliness Spans the Adult Lifespan but there is a Silver Lining

December 18, 2018

Moderate to severe loneliness can persist across adult lifespans, but UC San Diego School of Medicine researchers found it is particularly acute in three age periods: late-20s, mid-50s and late-80s. Wisdom proved a protective factor.

UC San Diego to Partner with New Allen Institute for Immunology

December 12, 2018

UC San Diego researchers join national effort to better understand human immune system as part of new Allen Institute of Immunology.

Targeted Cognitive Training Benefits Patients with Severe Schizophrenia

December 6, 2018

Researchers find that patients with severe, refractory schizophrenia benefit from targeted cognitive therapy, improving auditory and verbal outcomes and the way they process information.
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