August 29, 2016
August 29, 2016 —
Chronic fatigue syndrome (CFS) is a mysterious and maddening condition, with no cure or known cause. But researchers at the University of California San Diego School of Medicine, using a variety of techniques to identify and assess targeted metabolites in blood plasma, have identified a characteristic chemical signature for the debilitating ailment and an unexpected underlying biology: It is similar to the state of dauer, and other hypometabolic syndromes like caloric restriction, diapause and hibernation.
August 26, 2016
August 26, 2016 —
Researchers at University of California San Diego School of Medicine and Moores Cancer Center have identified RNA-based biomarkers that distinguish between normal, aging hematopoietic stem cells and leukemia stem cells associated with secondary acute myeloid leukemia (sAML), a particularly problematic disease that typically afflicts older patients who have often already experienced a bout with cancer.
August 24, 2016
August 24, 2016 —
While even the best wines eventually peak and turn to vinegar, a new study by researchers at University of California San Diego School of Medicine suggests a paradoxical trend in the mental health of aging adults: They seem to consistently get better over time.
August 19, 2016
August 19, 2016 —
Researchers at the University of California San Diego School of Medicine have found that a form of magnetic resonance imaging (MRI) that non-invasively measures fat density in the liver corresponds with histological (microscopic tissue analyses) responses in patients with nonalcoholic steatohepatitis (NASH).
August 10, 2016
August 10, 2016 —
In a study spanning molecular genetics, stem cells and the sciences of both brain and behavior, researchers at University of California San Diego, with colleagues at the Salk Institute for Biological Studies and elsewhere, have created a neurodevelopmental model of a rare genetic disorder that may provide new insights into the underlying neurobiology of the human social brain.
August 10, 2016
August 10, 2016 —
In a study spanning molecular genetics, stem cells and the sciences of both brain and behavior, researchers at University of California San Diego, with colleagues at the Salk Institute for Biological Studies and elsewhere, have created a neurodevelopmental model of a rare genetic disorder that may provide new insights into the underlying neurobiology of the human social brain.
July 21, 2016
July 21, 2016 —
In recognition of the Institutional Research and Academic Career Development Award (IRACDA) program at the University of California San Diego, which provides mentored training to postdocs in biomedical sciences, the National Institutes of Health has renewed its grant funding, lengthened the term and increased the number of supported postdoctoral scholars.
July 13, 2016
July 13, 2016 —
The majority of cases of autism spectrum disorder (ASD) are unknown. In a paper published in the journal Molecular Psychiatry, researchers at the University of California San Diego School of Medicine, with colleagues across the nation and world, have created a “mini-brain” model, derived from persons with a particular form of idiopathic ASD characterized by over-sized brains, revealing a defective molecular pathway during brain development that results in early neuronal overgrowth and dysfunctional cortical networks.
July 5, 2016
July 5, 2016 —
Researchers at University of California San Diego School of Medicine say tiny micro-vesicle structures used by neurons and other cells to transport materials internally or dispose of them externally carry tell-tale proteins that may help to predict the likelihood of mild cognitive impairment (MCI) developing into full-blown Alzheimer’s disease (AD).
June 10, 2016
June 10, 2016 —
Researchers at the University of California San Diego School of Medicine, with colleagues in Pennsylvania and China, report that not only are there distinct differences in key cellular processes and molecular signatures between rheumatoid arthritis (RA) and osteoarthritis (OA) but, more surprisingly, there are joint-specific differences in RA. The findings help explain why drugs treating RA vary in effect and provide a potential new template for precisely targeting treatment for each and every ailing joint.
