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News Archive - Mario Aguilera

‘SUMO’ Research at UC San Diego Wrestles with New Way to Read Cellular Function

November 21, 2017

University of California San Diego researchers in the Department of Chemistry and Biochemistry and in the Section of Cell and Developmental Biology have “got mail”—of the cellular sort. They know that cells have elaborate “addressing” functions that “send” proteins to the correct compartment, but they are now learning how cells “’write” the addresses and then “read” them. This is important because cellular function depends on each molecule in the cell being where it is supposed to be. But, often, protein molecules are not made in the compartment where they eventually need to function. In a paper recently published in Nature Communications, Professor Elizabeth Komives, chemistry and biochemisty, and Associate Professor Eric Bennett, cell and developmental biology, outline their research.

Researchers Discover New Pathway for Handling Stress

November 6, 2017

Researchers at the University of California San Diego studying how animals respond to infections have found a new pathway that may help in tolerating stressors that damage proteins. Naming the pathway the Intracellular Pathogen Response, or “IPR,” the scientists say it is a newly discovered way for animals to cope with certain types of stress and attacks, including heat shock.

UC San Diego Researchers Solve Mystery of Oxygenation Connections in the Brain

October 26, 2017

Scientists have known that areas of the brain with similar functions—even those in different brain hemispheres—connect to share signals when the body rests, but they haven’t known how this “resting-state connectivity” occurs. Now, scientists in the Neurophysics Laboratory at the University of California San Diego may have the answer.

UC San Diego Researchers Solve Mystery of Oxygenation Connections in the Brain

October 26, 2017

Scientists have known that areas of the brain with similar functions—even those in different brain hemispheres—connect to share signals when the body rests, but they haven’t known how this “resting-state connectivity” occurs. Now, scientists in the Neurophysics Laboratory at the University of California San Diego may have the answer.

Mutant Gene Found to Fuel Cancer-Promoting Effects of Inflammation

October 23, 2017

A study by UC San Diego biologists uncovered a new mechanism linking a human gene’s function to chronic inflammation and cancer. Through large-scale genomic analyses, they discovered that “mutant p53” amplifies the impact of inflammation, leading to increases in cancer. Thus, rather than fighting tumor growth, mutant forms of p53 appear to be tapping into the body’s immune response system to fuel pro-inflammatory responses that increase cancer growth.

Pair of Discoveries Illuminate New Paths to Flu and Anthrax Treatments

October 17, 2017

Two recent studies led by UC San Diego biologists have set the research groundwork for new avenues to treat influenza and anthrax poisoning. Published in PLOS Pathogens, the studies from Professor Ethan Bier’s laboratory used a series of experiments to identify key pathways and mechanisms previously unknown or overlooked in the body’s defenses, and possible treatments already developed.

Luring Hornets: Scientists Unlock Sex Pheromone of Notorious Honey Bee Predator

October 13, 2017

Biologists have developed a solution for controlling the invasive Asian hornet Vespa velutina based on the insect’s natural chemical mating instincts. They deciphered the Asian hornet’s sex pheromone and devised a method of luring males into traps baited with synthesized versions of the pheromones. Vespa velutina has recently spread its presence with invasions in Europe and Korea, posing risks to honey bees, humans and related economics.

UC San Diego Scientists Garner National High-Risk, High-Reward Awards

October 5, 2017

Emma Farley, an assistant professor at UC San Diego’s Division of Biological Sciences and School of Medicine, has been awarded the NIH Director’s New Innovator Award. Melissa Gymrek, an assistant professor in the School of Medicine and Department of Computer Science and Engineering, will receive the NIH Director’s Early Independence Award.

UC San Diego Scientists Garner National High-Risk, High-Reward Awards

October 5, 2017

Emma Farley, an assistant professor at UC San Diego’s Division of Biological Sciences and School of Medicine, has been awarded the NIH Director’s New Innovator Award. Melissa Gymrek, an assistant professor in the School of Medicine and Department of Computer Science and Engineering, will receive the NIH Director’s Early Independence Award.

UC San Diego Researchers Explain the Mechanism of Asexual Reproduction in Freshwater Flatworms

September 25, 2017

Freshwater planarians, found around the world and commonly known as “flatworms,” are famous for their regenerative prowess. Through a process called “fission,” planarians can reproduce asexually by simply tearing themselves into two pieces— a head and a tail—which then go on to form two new worms within about a week.
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