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News Archive - Mario Aguilera

Pesticide Cocktail Can Harm Honey Bees

April 10, 2019

A series of tests conducted over several years by UC San Diego scientists have shown for the first time that the pesticide Sivanto could pose a range of threats to honey bees depending on seasonality, bee age and use in combination with common chemicals such as fungicides.

Next-generation Gene Drive Arrives

April 9, 2019

Scientists developed a new version of a gene drive that spreads favorable genetic variants, also known as “alleles,” throughout a population. The new “allelic drive” is equipped with a guide RNA that directs CRISPR to cut undesired variants of a gene and replace them with a preferred version.

Researchers Discover a New Mechanism Used by Bacteria to Evade Antibiotics

March 7, 2019

UC San Diego researchers have discovered an unexpected mechanism that allows bacteria to defend themselves against antibiotics, a finding that could lead to retooled drugs to treat infectious diseases.

Foreign Bees Monopolize Prize Resources in Biodiversity Hotspot

February 20, 2019

New research reveals that foreign honey bees often account for more than 90 percent of pollinators observed visiting flowers in San Diego, a global biodiversity hotspot. The monopoly may strongly affect species that are foundational to the stability of the region’s plant-pollinator interactions.

Opposite Effect: Protein Widely Known to Fight Tumors Also Boosts Cancer Growth

January 31, 2019

UC San Diego researchers studying p53, the heralded cancer-fighting “guardian of the genome,” found that the human protein also plays a role in promoting tumors, in addition to suppressing them.

UC San Diego Researchers First to Use CRISPR/Cas9 to Control Genetic Inheritance in Mice

January 23, 2019

Using active genetics technology, biologists have developed the world’s first CRISPR/Cas9-based approach to control genetic inheritance in a mammal. The achievement in mice lays the groundwork for further advances based on this technology, including biomedical research on human disease.

New CRISPR-based Technology Developed to Control Pests with Precision-guided Genetics

January 8, 2019

Using CRISPR, researchers developed a way to suppress insects, including those that ravage crops and transmit deadly diseases. The technology alters genes for sex determination and fertility. When eggs are introduced, only sterile males emerge, resulting in a low-cost method of controlling pests.

UC San Diego Awarded $2 Million to Advance Algae-based Renewable Polymers

December 17, 2018

UC San Diego scientists have been granted $2 million to develop new methods for manufacturing products based on algae. Biologist Stephen Mayfield will lead efforts to develop novel platforms to produce biologically based monomers that will be used to manufacture renewable and biodegradable products.

Biologists Discover Source for Boosting Tumor Cell Drug Sensitivity

October 29, 2018

Biologists at UC San Diego have discovered a new way of re-sensitizing drug-resistant human tumor cells to the potency of DNA-damaging agents, the most widely used group of cancer drugs. In a new study, they describe how a human gene known as Schlafen 11 controls the sensitivity of tumor cells to DDAs. Their research may pave the way to new strategies to overcome chemotherapeutic drug resistance.

Taking out the (Life-threatening) Garbage: Bacteria Eject Trash to Survive

September 27, 2018

Scientists have known that bacteria produce small spherical versions of themselves. Lacking basic materials to reproduce or function like normal cells, the natural role of minicells—which protrude like budding balloons off the ends of bacteria—has remained a mystery. Now, researchers at UC San Diego have demonstrated for the first time that minicells play a key function in the survival of bacteria.
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