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News Archive - Debra Kain

UC San Diego Researcher Receives $2.5 million Award from the National Institute on Drug Abuse

July 24, 2012

Dr. Davey Smith, associate professor of medicine at the UC San Diego School of Medicine and the VA San Diego Health System is one of three recipients of the 2012 Avant-Garde Award for HIV/AIDS research.

Novel Anti-Malarial Drug Target Identified

July 19, 2012

An international team of scientists, led by researchers from the department of pediatrics at the UC San Diego School of Medicine, have identified the first reported inhibitors of a key enzyme involved in survival of the parasite responsible for malaria. Their findings, which may provide the basis for anti-malarial drug development, are currently published in the online version of the Journal of Medicinal Chemistry.

Epigenetics Alters Genes in Rheumatoid Arthritis

July 3, 2012

Researchers at the University of California, San Diego – led by Gary S. Firestein, MD, professor in the Division of Rheumatology, Allergy and Immunology at UC San Diego School of Medicine – investigated a mechanism usually implicated in cancer and in fetal development, called DNA methylation, in the progression of rheumatoid arthritis (RA). They found that epigenetic changes due to methylation play a key role in altering genes that could potentially contribute to inflammation and joint damage.

Researchers Block Pathway to Cancer Cell Replication

July 3, 2012

Research suggests that patients with leukemia sometimes relapse because standard chemotherapy fails to kill the self-renewing leukemia initiating cells, often referred to as cancer stem cells. In such cancers, the cells lie dormant for a time, only to later begin cloning, resulting in a return and metastasis of the disease. One such type of cancer is called pediatric T cell acute lymphoblastic leukemia, or T-ALL, often found in children, who have few treatment options beyond chemotherapy.

Statins Shown to Cause Fatigue

June 11, 2012

In a study of more than 1,000 adults, researchers at the University of California, San Diego, found that individuals taking cholesterol-lowering statin drugs are more likely than non-users to experience decreased energy, fatigue upon exertion, or both. The researchers suggest that these findings should be taken into account by doctors when weighing risk versus benefit in prescribing statins.

UC San Diego to Study Accelerated Aging in Schizophrenia

June 5, 2012

Researchers at the Stein Institute for Research on Aging at the University of California, San Diego have received a $4 million grant from the National Institute of Mental Health (NIMH), part of the National Institutes of Health, to study accelerated biological aging in schizophrenia.

Drug Found for Parasite that is Major Cause of Death Worldwide

May 21, 2012

Research by a collaborative group of scientists from UC San Diego School of Medicine, UC San Francisco and Wake Forest School of Medicine has led to identification of an existing drug that is effective against Entamoeba histolytica. This parasite causes amebic dysentery and liver abscesses and results in the death of more than 70,000 people worldwide each year.

Early Biomarker for Pancreatic Cancer Identified

May 15, 2012

Researchers at the University of California, San Diego School of Medicine and Moores Cancer Center have identified a new biomarker and therapeutic target for pancreatic cancer, an often-fatal disease for which there is currently no reliable method for early detection or therapeutic intervention.

Novel Approaches to Treating Alzheimer’s Disease Include Early Intervention

May 15, 2012

Researchers at the Comprehensive Alzheimer’s Program at the University of California, San Diego School of Medicine have announced two new clinical trials for patients with either mild to moderate Alzheimer’s disease (AD) and one trial for Mild Cognitive Impairment.

Smoked Cannabis Reduces Some Symptoms of Multiple Sclerosis

May 14, 2012

A clinical study of 30 adult patients with multiple sclerosis (MS) at the University of California, San Diego School of Medicine has shown that smoked cannabis may be an effective treatment for spasticity – a common and disabling symptom of this neurological disease.
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