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Bioengineers: Matrix Stiffness is an Essential Tool in Stem Cell Differentiation

August 12, 2014

Bioengineers at the University of California, San Diego have proven that when it comes to guiding stem cells into a specific cell type, the stiffness of the extracellular matrix used to culture them really does matter. When placed in a dish of a very stiff material, or hydrogel, most stem cells become bone-like cells. By comparison, soft materials tend to steer stem cells into soft tissues such as neurons and fat cells. The research team, led by bioengineering professor Adam Engler, also found that a protein binding the stem cell to the hydrogel is not a factor in the differentiation of the stem cell as previously suggested. The protein layer is merely an adhesive, the team reported Aug. 10 in the advance online edition of the journal Nature Materials.

Benefunder to Launch New Funding Channel for Higher Education Research

August 11, 2014

Benefunder, a San Diego-based philanthropic research funding platform for higher education institutions, and the University of California, San Diego, recognized as one of the top 15 research universities worldwide, have signed a Memorandum of Understanding (MOU) to embark on a two-year pilot program. The long-term goal of the partnership between UC San Diego and Benefunder is to allow junior and senior faculty in diverse disciplines to create funding relationships with private supporters from across the country, and generate one-time and recurring donations to fund their work and vision.

Novel Study Maps Infant Brain Growth In First Three Months of Life Using MRI Technology

August 11, 2014

A recent study conducted by researchers at the University of California, San Diego School of Medicine and the University of Hawaii demonstrates a new approach to measuring early brain development of infants, resulting in more accurate whole brain growth charts and providing the first estimates for growth trajectories of subcortical areas during the first three months after birth.

Clinical Trial Evaluates Safety of Stem Cell Transplantation in Spine

August 11, 2014

Researchers at the University of California, San Diego School of Medicine have launched a clinical trial to investigate the safety of neural stem cell transplantation in patients with chronic spinal cord injuries. This Phase I clinical trial is recruiting eight patients for the 5-year study.

How Breast Cancer Usurps the Powers of Mammary Stem Cells

August 11, 2014

During pregnancy, certain hormones trigger specialized mammary stem cells to create milk-producing cells essential to lactation. Scientists at the University of California, San Diego School of Medicine and Moores Cancer Center have found that mammary stem cells associated with the pregnant mammary gland are related to stem cells found in breast cancer.

Target Identified For Rare Inherited Neurological Disease In Men

August 10, 2014

Researchers at University of California, San Diego School of Medicine have identified the mechanism by which a rare, inherited neurodegenerative disease causes often crippling muscle weakness in men, in addition to reduced fertility.

New Nano3 Microscope Will Allow High-Resolution Look Inside Cells

August 8, 2014

The University of California, San Diego’s Nanofabrication Cleanroom Facility (Nano3) is the first institution to obtain a novel FEI Scios dual-beam microscope, with an adaptation for use at cryogenic temperatures. The new microscope will enable research among a highly diverse user base, ranging from materials science to structural and molecular biology.

Designing Better Materials for the 21st Century

August 7, 2014

The U.S. Defense Department recently named Jian Luo, professor of nanoengineering and materials science and engineering at the University of California, San Diego as one of 10 new National Security Science and Engineering Faculty Fellows (NSSEFF). The award provides up to $3 million over five years to develop a new materials design tool called interfacial phase diagrams.

Dramatic Growth of Grafted Stem Cells in Rat Spinal Cord Injuries

August 7, 2014

Building upon previous research, scientists at the University of California, San Diego School of Medicine and Veteran’s Affairs San Diego Healthcare System report that neurons derived from human induced pluripotent stem cells (iPSC) and grafted into rats after a spinal cord injury produced cells with tens of thousands of axons extending virtually the entire length of the animals’ central nervous system.

Learn to code while playing Minecraft

August 5, 2014

A team of computer scientists at the University of California, San Diego, has developed a software package that allows users to learn how to program while playing the popular video game Minecraft. LearnToMod, which allows users to make a wide range of modifications to Minecraft, is available for pre-order for $30. The software will be delivered in October.
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