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SDSC Simulations Reveal How a Heart Drug Molecular Switch Is Turned On and Off

March 6, 2018

The study, published in the March 5 online edition of the Proceedings of the National Academy of Sciences (PNAS), describes how the supercomputing power of Gordon, Comet, and GPU clusters, all based at the San Diego Supercomputer Center at UC San Diego, were used with improved accelerated molecular dynamics (aMD) or Gaussian aMD (GaMD) to simulate the merger of a G-protein “mimetic nanobody” to a G-protein-coupled receptor (GPCR), the largest and most diverse group of membrane receptors in animals, plants, fungi, and protozoa.

Engineers Develop Most Efficient Red light-activated Optogenetic Switch for Mammalian Cells

March 5, 2018

A team of researchers has developed a light-activated switch that can turn genes on and off in mammalian cells. This is the most efficient so-called “optogenetic switch” activated by red and far-red light that has been successfully designed and tested in animal cells—and it doesn’t require the addition of sensing molecules from outside the cells.

Koman Family Outpatient Pavilion Opens at UC San Diego Health on March 12

March 5, 2018

On March 12, 2018, UC San Diego Health will welcome its first patients to the Koman Family Outpatient Pavilion. Located on the La Jolla campus, the new 156,000-square-foot facility represents the most recent addition to the university’s world-class medical campus. In the past five years, UC San Diego Health has invested more than $1.3 billion dollars in patient care facilities for the community.

SDSC’s Health CI Division Now Meets NIST CUI Compliance Requirements

March 5, 2018

The Health Cyberinfrastructure Division of the San Diego Supercomputer Center (SDSC) at the University of California San Diego has expanded its cloud offerings to include a Controlled Unclassified Information (CUI)-compliant environment that is now available to researchers working with government contracts and grants.

Polygenic Risk Score May Identify Alzheimer’s Risk in Younger Populations

March 5, 2018

For the first time, an international team of scientists, led by researchers at University of California San Diego School of Medicine, have determined that an Alzheimer’s disease (AD) polygenic risk score can be used to correctly identify adults with mild cognitive impairment (MCI) who were only in their 50s. MCI is considered a precursor to AD.

How a Yeast Cell Helps Crack Open the “Black Box” Behind Artificial Intelligence

March 5, 2018

UC San Diego School of Medicine researchers developed a visible neural network and used it to build DCell, a virtual model of a functioning brewer’s yeast cell. To do this, they amassed all knowledge of cell biology in one place and created a hierarchy of these cellular components. Then they mapped standard machine learning algorithms to this knowledgebase. DCell can be viewed at d-cell.ucsd.edu. The technical details are published March 5 in Nature Methods.

Lyft and UC San Diego Establish First Comprehensive University Partnership in Nation

March 1, 2018

The University of California San Diego and Lyft, the fastest growing rideshare company in the U.S., have forged a partnership aimed at developing innovative commuter solutions to meet the university’s evolving transportation needs.

UC San Diego Scientists: Is a Dark Particle the ‘Dark Horse’ of Dark Matter?

March 1, 2018

Dark Matter is more than the name of a show on the SyFy channel. It's the stuff that makes up about 85 percent of the universe. But because dark matter does not emit light or energy, scientists cannot directly observe it-and it remains one of the biggest mysteries of science.

UC San Diego Hosts Its First Virtual Reality, Augmented Reality Hackathon

March 1, 2018

Anish Kannan, a fourth year computer science student at UC San Diego, had no interest in virtual reality (VR) until one fateful hackathon four years ago.

Scripps Joins Mission to Understand a Major Southern Ocean Climate Influencer

March 1, 2018

Climate scientists at Scripps Institution of Oceanography at the University of California San Diego are joining colleagues at other institutions in the United States and Australia to get an unprecedented look at a region with the most tempestuous weather on Earth.
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