October 28, 2022
In animal models, UC San Diego researchers found that intensive physical therapy in tandem with implanted neural stem cells increased tissue growth, repair and functionality in spinal cord injuries more than those treatments alone.
August 12, 2014
…it comes to guiding stem cells into a specific cell type, the stiffness of the extracellular matrix used to culture them really does matter. When placed in a dish of a very stiff material, or hydrogel, most stem cells become bone-like cells. By comparison, soft materials tend to steer stem…
March 17, 2021
By studying how different pluripotent stem cell lines build muscle, researchers have for the first time discovered how epigenetic mechanisms can be triggered to accelerate muscle cell growth, providing new insights for developing therapies for muscle disease, injury and atrophy.
August 2, 2012
…Medicine, a new, state-of-the-art stem cell research facility dedicated to research and finding cures and therapies for some of society’s most devastating diseases. This new “collaboratory” brings together UC San Diego’s research partners on the mesa in a way that allows for unique collaborations that otherwise may not be possible.…
March 7, 2023
UC San Diego researchers delve deep into the unknown cause of pediatric acute myeloid leukemia to identify a gene splicing dysregulation and potential target for treating the disease, which often becomes treatment-resistant.
February 11, 2015
To better understand these cellular changes and how they influence the progression and severity of glaucoma, researchers at University of California, San Diego School of Medicine and Shiley Eye Institute turned to a mouse model of the disease. Their study, published Feb. 10 in The Journal of Neuroscience, reveals how…
August 11, 2014
Researchers at the University of California, San Diego School of Medicine have launched a clinical trial to investigate the safety of neural stem cell transplantation in patients with chronic spinal cord injuries. This Phase I clinical trial is recruiting eight patients for the 5-year study.
February 5, 2019
Using a leading-edge technique, UC San Diego School of Medicine researchers defined the cell types in both newborn and adult human testes and identified biomarkers for spermatogonial stem cells, opening a path for new strategies to treat male infertility.
April 2, 2015
Cells of the intestine, liver and pancreas are difficult to produce from stem cells. Writing in Cell Stem Cell April 2, researchers at University of California, San Diego School of Medicine have discovered that chromosomes in laboratory stem cells open slowly over time, in the same sequence that occurs during…
November 14, 2011
Spotlight on Faculty Research: Stem Cell Shu Chien University Professor & Chair Dr. Chien and his colleagues have developed an array system 〈with thousands of combinations〉 that allows the rapid determination of the optimum physical and chemical conditions that direct the differentiation of stem cells into specific cell types. The…
