November 22, 2022
The Highly Cited Researchers list identifies and celebrates exceptional researchers who are having a significant impact on the research community as evidenced by the rate at which their work is being cited by their peers. UC San Diego ranks 8th in the world for 2022.
April 4, 2019
An international team of scientists led by researchers at University of California San Diego School of Medicine employed an array of next-generation sequencing and gene-editing tools, such as CRISPR, to map the molecular dependencies – and thus vulnerabilities – of pancreatic cancer stem cells.
December 6, 2011
Researchers at UC San Diego’s Department of Chemistry and Biochemistry, in collaboration with several universities in the U.S., United Kingdom, and Poland, have developed a new picture of how kinesin molecules move along microtubules, or tiny biological train tracks – and how they sometimes come to a halt, causing diseases…
May 19, 2016
Researchers at University of California San Diego School of Medicine and Sanford Burnham Prebys Medical Discovery Institute have discovered that high levels of the protein p62 in human liver samples are strongly associated with cancer recurrence and reduced patient survival. In mice, they also found that p62 is required for…
September 13, 2018
Researchers at University of California San Diego School of Medicine have discovered using mice and human clinical specimens, that caspase-2, a protein-cleaving enzyme, is a critical driver of non-alcoholic steatohepatitis (NASH), a chronic and aggressive liver condition. By identifying caspase-2’s critical role, they believe an inhibitor of this enzyme could…
July 17, 2024
UC San Diego’s Skaggs School of Pharmacy and Pharmaceutical Sciences ranks seventh in the nation for research funding, securing over $34 million in grants to tackle pressing health issues like malaria, infant health, and more.
March 27, 2013
An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, says a key protein in Schwann cells performs a critical, perhaps overarching, role in regulating the recovery of peripheral nerves after injury. The discovery has implications for improving the treatment of neuropathic…
August 25, 2020
UC San Diego researchers engineered fluorescent tools that combine the gene editing technique CRISPR and biosensor technologies to look inside cells in a whole new way. Their findings show that a major protein that binds to the signaling molecule cAMP can form membraneless organelles in human cells.
November 8, 2017
Chronic inflammation is known to drive many cancers, especially liver cancer. Researchers have long thought that’s because inflammation directly affects cancer cells, stimulating their division and protecting them from cell death. But University of California San Diego School of Medicine researchers have now found that chronic liver inflammation also promotes…
July 25, 2018
In a study published online July 25 in the journal Nature, University of California San Diego School of Medicine researchers identified a signaling pathway that activates the NLRP3 inflammasome implicated in several severe chronic inflammatory disorders.
