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Your search for “pharmacology” returned 290 results

UC San Diego Health Researchers Join Pancreatic Cancer “Dream Team”

November 9, 2015

In an effort to advance research on one of the deadliest forms of cancer, University of California, San Diego School of Medicine researchers Andrew Lowy, MD, and Tannishtha Reya, PhD, have been recruited for their expertise in preclinical modeling, clinical trials and stem cell biology to join a “dream team”…

‘Leaky’ Activity of Mutated Enzyme Underlies Neurodegenerative Disease

October 3, 2022

UC San Diego study finds enhanced PKCγ activity drives spinocerebellar ataxia type 14; suggests inhibiting the enzyme may have therapeutic potential

Building Robust Collaborations to ‘ATTACK’ Future Pandemics

January 18, 2022

Six University of California campuses, in coordination with two national labs and more than one dozen industry partners, have formed the University of California-National Labs Antiviral Treatments Targeting All Coronaviruses and Key RNA viruses Consortium to prepare for and prevent future pandemics.

How Cells Repurpose their Garbage Disposal Systems to Promote Inflammation

September 18, 2018

Researchers at University of California San Diego School of Medicine have unraveled new insights into the way cells leverage G-protein-coupled receptors (GPCRs) and their cellular waste disposal systems to control inflammation. The findings, published September 18 in Cell Reports, suggest some existing cancer drugs that inhibit these cellular activities might…

Meet Dr. Brookie Best, Dean of the Skaggs School of Pharmacy and Pharmaceutical Sciences

August 11, 2022

…maternal/fetal and pediatric clinical pharmacology, exploring the effects of anti-HIV drugs in pregnant women, children and non-pregnant adults, and drugs used to treat Kawasaki disease, the leading cause of acquired heart disease in children. She has authored more than 130 peer-reviewed papers, lectured on maternal and pediatric drug therapeutics at…

3D Human Skin Maps Aid Study of Relationships Between Molecules, Microbes and Environment

March 30, 2015

Researchers at the University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences produced 3D maps of molecular and microbial variations across the body. These maps provide a baseline for studies of the interplay between the molecules that make up our skin, our microbiomes, our personal hygiene routines…

SDSC Supercomputer Modeling Reveals Acrobatics of CRISPR-Cas9 Technology

September 12, 2016

A team led by researchers at the University of California San Diego has captured in step-by-step atomic detail the surgical editing of DNA strands by CRISPR-Cas9, the innovative gene-splicing technology that in recent years has transformed the field of genetic engineering.

Nanoengineers Receive $4.3M From NIH To Continue Studies Using Plant Viruses To Treat Cancer

October 17, 2022

Researchers led by Nicole Steinmetz, professor of nanoengineering at the University of California San Diego, have received $4.3 million in grants from the National Institutes of Health (NIH) to advance their research using plant viruses to develop cancer immunotherapies.

Pictured Together for the First Time: a Chemokine and its Receptor

January 22, 2015

Researchers at University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences and the Bridge Institute at the University of Southern California report the first crystal structure of the cellular receptor CXCR4 bound to an immune signaling protein called a chemokine. The structure answers longstanding questions about a…

The Connection Between Oxygen and Diabetes

June 5, 2014

Researchers at the University of California, San Diego School of Medicine have, for the first time, described the sequence of early cellular responses to a high-fat diet, one that can result in obesity-induced insulin resistance and diabetes. The findings also suggest potential molecular targets for preventing or reversing the process.

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