September 14, 2021
Using a virus that grows in black-eyed pea plants, researchers developed a new therapy that could keep metastatic cancers from spreading to the lungs, as well as treat established tumors in the lungs.
May 15, 2012
Researchers at the University of California, San Diego School of Medicine and Moores Cancer Center have identified a new biomarker and therapeutic target for pancreatic cancer, an often-fatal disease for which there is currently no reliable method for early detection or therapeutic intervention.
February 19, 2020
UC San Diego bioengineers developed a control system that could make CAR T-cell therapy safer and more powerful when treating cancer. By programming CAR T cells to switch on when exposed to blue light, the researchers controlled the cells to destroy skin tumors in mice without harming healthy tissue
June 22, 2020
UC San Diego researchers uncovered in mice how IRE1α, a molecule involved in cells’ response to stress, determines whether macrophages promote inflammation in the tumor microenvironment. Inflammation is known to promote tumor growth, making IRE1α an attractive target for drug development.
December 3, 2018
Following the FDA’s approval of chimeric antigen receptor (CAR) T-cell therapies for the treatment of certain types of non-Hodgkin lymphomas, UC San Diego Health was the first medical center in San Diego to be certified to offer this type of immunotherapy outside of a clinical trial.
July 23, 2020
…intent of making combination immunotherapies more effective. “UC San Diego Health stepped up and made sure I got the next best thing,” said Thurman. “It’s literally a matter of life or death for me. None of the treatments I have undergone so far have worked. This is one of my…
November 28, 2018
High-tech surgical suites allow doctors to scan patients without either leaving the operating room.
October 8, 2015
…clinical research, the experimental immunotherapy treatment used on Matthew became commercially available for the first time. Paving the Path to Success Any great clinical accomplishment is built on a foundation of diverse contributions from others. Milestones in the preclinical development of Unituxin include the seminal work of scientists at The…
December 11, 2017
Researchers have identified a promising new strategy to fight infections and cancer. They uncovered a novel function for a protein known as “Runx3” that is key to the development of killer T cells—immune cells important for fighting infections and cancer. The researchers believe Runx3, if properly directed, could be combined…
November 1, 2016
Researchers at University of California San Diego School of Medicine and Mayo Clinic provide the first evidence that the Hedgehog signaling pathway is central to the formation of gastrointestinal stromal tumors (GIST), which are frequently driven by the KIT oncogene.
