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Your search for “immunotherapy” returned 94 results

DNA Mutations Shed in Blood Predicts Response to Immunotherapy in Patients with Cancer

October 1, 2017

…help predict response to immunotherapy by measuring the number of mutations in circulating tumor DNA using a simple blood test,” said Yulian Khagi, MD, UC San Diego Moores Cancer Center fellow and first author. “Immunotherapy can result in serious side effects, and therefore being able to predict who will respond…

New Precision Immunotherapy Clinic Matches Patients to Latest Cancer Therapies

October 17, 2019

…the newly established Precision Immunotherapy Clinic. Photo by Yadira Galindo/UC San Diego Health New Precision Immunotherapy Clinic Matches Patients to Latest Cancer Therapies Using a personalized approach, Moores Cancer Center at UC San Diego Health employs genetic profiling to treat patients who have not responded to, or relapsed from, standard…

SDSC’s Comet Supercomputer Helps Benchmark Cancer Immunotherapy Tool

March 24, 2020

…which aims to improve immunotherapy outcomes by identifying more effective personalized treatments. Led by postdoctoral researcher Didier Devaurs, the Rice researchers recently published their evaluation of DINC in the BMC Molecular and Cell Biology journal. The most significant result is that their molecular docking approach can make predictions of molecular…

Immunotherapy Research for Head and Neck Cancers Gets Boost from V Foundation Grant

November 27, 2017

…break resistance to cancer immunotherapy has been awarded a V Foundation for Cancer Research translational grant of $600,000 over three years. Judith Varner, PhD, will lead the multi-year study at UC San Diego School of Medicine. Led by Judith A. Varner, PhD, professor in the departments of Pathology and Medicine…

Drug Combination May Improve Impact of Immunotherapy in Head and Neck Cancer

September 21, 2017

Checkpoint inhibitor-based immunotherapy has been shown to be very effective in recurrent and metastatic head and neck cancer but only in a minority of patients. University of California San Diego School of Medicine researchers may have found a way to double down on immunotherapy’s effectiveness. In a paper published in…

Rock Tour “Text2Give” Supports Immunotherapy at UC San Diego Health

April 19, 2017

…after participating in an immunotherapy clinical trial at Moores Cancer Center at UC San Diego Health, he was declared cancer-free in July 2016. To give back, Rockett is now asking concert-goers to join him in supporting immunotherapy at Moores Cancer Center. At U.S. stops on the Poison tour now through…

A New Strategy to Transform Liver Cancer Immunotherapy

December 7, 2021

In recent years, tumor immunotherapy has emerged as a highly promising and much-touted oncological approach. It is based on using humanized antibodies called immune checkpoint inhibitors (ICIs) to block the cellular pathways that inhibit the activity of T lymphocytes, a type of immune system cells that help protect the body…

Inhibiting Enzyme Helps Cancer Immunotherapy Work Better

August 3, 2020

Cancer immunotherapy — a treatment that better enables a patient’s own immune system to attack tumors — has shown great potential against some cancers. Yet immunotherapy doesn’t work against all tumor types, and many patients who initially respond later develop resistance and relapse. Researchers at University of California San Diego…

Study Reveals New Role for Hippo Pathway in Suppressing Cancer Immunity

December 1, 2016

…in improving efficiency of immunotherapy drugs. “Before our study, no one knew that the Hippo pathway was regulating immunogenicity,” said first author Toshiro Moroishi, MD, PhD, postdoctoral researcher at UC San Diego Moores Cancer Center. “LATS1/2 deletion in cancer cells improves tumor immunogenicity, leading to the destruction of cancerous cells…

UC San Diego Biologists Discover Process That Neutralizes Tumors

July 10, 2018

…patient will respond to immunotherapy. Ideally, the immune system identifies tumors as threatening elements and deploys immune cells (T cells) to find and kill them. However, tumor cells have evolved to employ a protein called PD-L1 to blind T cells from carrying out their functions and evade immune defenses. PD-L1…

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