November 25, 2013
Researchers at the University of California, San Diego School of Medicine have successfully targeted T lymphocytes – which play a central role in the body’s immune response – with another type of white blood cell engineered to synthesize and deliver bits of non-coding RNA or microRNA (miRNA).
August 18, 2016
Concerns over the Zika virus have focused on pregnant women due to mounting evidence that it causes brain abnormalities in developing fetuses. However, new research in mice suggests that certain adult brain cells may be vulnerable to infection as well. Among these are populations of cells that serve to replace…
January 13, 2022
According to a 2021 World Health Organization report, the global COVID-19 pandemic caused an increase in tuberculosis (TB) deaths – 1.5 million in 2020 versus 1.4 million in 2019 – due to a lack of efficient diagnosis and treatment.
November 27, 2013
Using advanced methodologies that pit drug compounds against specific types of malaria parasite cells, an international team of scientists, including researchers at the University of California, San Diego School of Medicine and the Genomics Institute of the Novartis Research Foundation, have identified a potential new weapon and approach for attacking…
October 17, 2019
…Schoenberger, a professor of immunology at the La Jolla Institute for Immunology (LJI), to confirm his suspicions by testing Levine’s white blood cells for an immune response against mutations identified during his tumor sequencing. “While immunotherapy is not approved for Gordon’s molecular tumor profile, we can sometimes use drugs off-label…
September 10, 2018
Macrophages are immune cells that are supposed to protect the body from infection by viruses and bacteria. Yet Zika virus preferentially infects these cells. Researchers at University of California San Diego School of Medicine have now unraveled how the virus shuts down the genes that make macrophages function as immune…
June 23, 2022
A $10 million grant over four years will support further examination of a national study looking at COVID-19 vaccination safety during pregnancy and immune response pre-and post-delivery for both mom and baby.
April 21, 2023
UC San Diego researchers describe a key player in the defense mechanism that safeguards against excessive insulin in the body, which can be as harmful as too little.
July 21, 2015
Roughly 20 to 30 percent of patients with hepatitis C virus (HCV) are also infected with human immunodeficiency virus type 1 (HIV). Both blood-borne viruses share the same modes of transmission, but many HCV medications currently have significant limitations due to adverse interactions with HIV treatments. Researchers at University of…
June 29, 2022
Researchers are expanding their understanding of unique immune “memory” cells equipped to remember malicious invaders. They developed an atlas that describes tissue-resident memory cells in diverse settings, boosting prospects for new immune defense strategies at vulnerable infection sites.