August 20, 2015
An international team of scientists headed by biologists at UC San Diego has discovered that an important class of stem cells known as human “induced pluripotent stem cells,” or iPSCs, which are derived from an individual’s own cells, can be differentiated into various types of functional cells with different fates…
June 9, 2016
Cancer stem cells are like zombies — even after a tumor is destroyed, they can keep coming back. These cells have an unlimited capacity to regenerate themselves, making more cancer stem cells and more tumors. Researchers at University of California San Diego School of Medicine have now unraveled how pre-leukemic…
August 31, 2016
Researchers at the University of California San Diego have discovered an easy and efficient way to coax human pluripotent stem cells to regenerate bone tissue—by feeding them adenosine, a naturally occurring molecule in the body. The stem-cell-derived bone tissue helped repair cranial bone defects in mice without developing tumors or…
October 24, 2016
There are many unanswered questions about the mechanisms that contribute to the onset of type 1 diabetes. Researchers at University of California San Diego School of Medicine hope to answer some of them with two Type 1 Diabetes Special Statutory Funding Program grants from the National Institutes of Health totaling…
October 27, 2016
Acute myeloid leukemia (AML) is an aggressive cancer known for drug resistance and relapse. In an effort to uncover new treatment strategies, researchers at University of California San Diego School of Medicine and Moores Cancer Center discovered that a cell surface molecule known as CD98 promotes AML. The study also…
August 28, 2017
More than one-and-a-half years after implantation, researchers at University of California San Diego School of Medicine and the San Diego Veterans Administration Medical Center report that human neural stem cells (NSCs) grafted into spinal cord injuries in laboratory rats displayed continued growth and maturity, with functional recovery beginning one year…
February 28, 2018
Science continues to peel away layers of the skin microbiome to reveal its protective properties. In a study published in Science Advances on February 28, University of California San Diego School of Medicine researchers report a potential new role for some bacteria on the skin: protecting against cancer.
December 4, 2018
In lab and mouse experiments, UC San Diego School of Medicine researchers developed a method to leverage B cells to manufacture and secrete tumor-suppressing microRNAs.
January 16, 2020
Two different UC San Diego research teams identified the same molecule — αvβ5 integrin — as Zika virus’ key to brain cell entry. They found ways to take advantage of the integrin to both block Zika virus from infecting cells and turn it into something good: a way to shrink…
July 2, 2021
UC San Diego studies using human cell lines and tumors grown in mice provide early evidence that inhibiting RNA-binding proteins, a previously overlooked family of molecules, might provide a new approach for treating some cancers.
