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Your search for “Transplant” returned 230 results

The Coming of Age of Stem Cell Therapy

October 30, 2014

…a treatment in which transplanted neural stem cells will develop into new neurons that bridge the gap created by an injury, replace severed or lost nerve connections and restore at least some motor and sensory function. Also last month, researchers at UC San Diego Moores Cancer Center and the Sanford…

Researchers Block Pathway to Cancer Cell Replication

July 3, 2012

Research suggests that patients with leukemia sometimes relapse because standard chemotherapy fails to kill the self-renewing leukemia initiating cells, often referred to as cancer stem cells. In such cancers, the cells lie dormant for a time, only to later begin cloning, resulting in a return and metastasis of the disease.…

Stem Cell Injections Improve Spinal Injuries in Rats

May 28, 2013

An international team led by researchers at the University of California, San Diego School of Medicine reports that a single injection of human neural stem cells produced neuronal regeneration and improvement of function and mobility in rats impaired by an acute spinal cord injury (SCI).

A Better Way to Track Emerging Cell Therapies Using MRIs

September 19, 2014

Researchers at the University of California, San Diego School of Medicine, University of Pittsburgh and elsewhere describe the first human tests of using a perfluorocarbon (PFC) tracer in combination with non-invasive magnetic resonance imaging (MRI) to track therapeutic immune cells injected into patients with colorectal cancer.

Epigenetic Driver of Glioblastoma Provides New Therapeutic Target

July 6, 2015

Using human tumor samples and mouse models, researchers at University of California, San Diego School of Medicine and Moores Cancer Center discovered that cancer stem cell properties are determined by epigenetic changes — chemical modifications cells use to control which genes are turned on or off.

Study Provides Hope for Some Human Stem Cell Therapies

August 20, 2015

An international team of scientists headed by biologists at UC San Diego has discovered that an important class of stem cells known as human “induced pluripotent stem cells,” or iPSCs, which are derived from an individual’s own cells, can be differentiated into various types of functional cells with different fates…

Body’s Own Gene Editing System Generates Leukemia Stem Cells

June 9, 2016

Cancer stem cells are like zombies — even after a tumor is destroyed, they can keep coming back. These cells have an unlimited capacity to regenerate themselves, making more cancer stem cells and more tumors. Researchers at University of California San Diego School of Medicine have now unraveled how pre-leukemic…

Researchers Use a Single Molecule to Command Stem Cells to Build New Bone

August 31, 2016

Researchers at the University of California San Diego have discovered an easy and efficient way to coax human pluripotent stem cells to regenerate bone tissue—by feeding them adenosine, a naturally occurring molecule in the body. The stem-cell-derived bone tissue helped repair cranial bone defects in mice without developing tumors or…

UC San Diego School of Medicine Researchers Receive $5 Million in Type 1 Diabetes Grants

October 24, 2016

There are many unanswered questions about the mechanisms that contribute to the onset of type 1 diabetes. Researchers at University of California San Diego School of Medicine hope to answer some of them with two Type 1 Diabetes Special Statutory Funding Program grants from the National Institutes of Health totaling…

Antibody Breaks Leukemia’s Hold, Providing New Therapeutic Approach

October 27, 2016

Acute myeloid leukemia (AML) is an aggressive cancer known for drug resistance and relapse. In an effort to uncover new treatment strategies, researchers at University of California San Diego School of Medicine and Moores Cancer Center discovered that a cell surface molecule known as CD98 promotes AML. The study also…

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