Don Cleveland Wins a Trifecta of Recognition
January 31, 2023
In the span of just a few weeks, Don Cleveland, a leading researcher in the study of neurodegenerative diseases like ALS and Alzheimer’s, has received three major awards.
Your search for “Therapy Target” returned 457 results
Out of Thin Air
August 27, 2020
…usually resolves with medical therapy, such as blood thinners. In some cases, however, blood clots do not go away or they recur. When this happens, the lungs experience harmful vascular changes that can result in pulmonary hypertension. One of the leading causes of right-sided heart failure, CTEPH can be deadly…
Shedding Light on Cancer Diversity and Resistance
February 21, 2017
A paradigm-changing study in the journal Nature by cancer researchers and computer scientists at UC San Diego and other institutions found that short fragments of circular DNA that encode cancer genes are far more common in cancer cells than previously believed.
Cancer Stem Cells Linked to Drug Resistance
April 20, 2014
Most drugs used to treat lung, breast and pancreatic cancers also promote drug-resistance and ultimately spur tumor growth. Researchers at the University of California, San Diego School of Medicine have discovered a biomarker called CD61 on the surface of drug-resistant tumors that appears responsible for inducing tumor metastasis by enhancing…
UC San Diego Sparks New Cancer-Focused Startup, Oncternal, with Exclusive Antibody License
May 2, 2016
Oncternal Therapeutics, a new cancer-focused biotechnology startup, has signed a wide-ranging licensing agreement with UC San Diego to develop and commercialize antibodies and antibody-related binding agents.
Center for AIDS Research Receives $15 Million Renewal Grant From NIH
April 3, 2023
The National Institute of Allergy and Infectious Diseases has awarded a five-year, $15.45 million grant to the San Diego Center for AIDS Research at UC San Diego, renewing support that extends back to an original establishing grant in 1994 at the height of the AIDS epidemic.
Blocking Tumor-Induced Inflammation Impacts Cancer Development
October 3, 2012
Researchers at the University of California, San Diego School of Medicine report the discovery of microbial–dependent mechanisms through which some cancers mount an inflammatory response that fuels their development and growth.
UC San Diego Researcher Gets $4 Million NCI Award to Study Cancer Drug Resistance, Spread
December 7, 2018
David Cheresh, Distinguished Professor at University of California San Diego School of Medicine, received $4.2 million National Cancer Institute Outstanding Investigator Award to continue his research into cancer’s ability to overcome stress, gain drug resistance and metastasize.
Flesh-Eating Infections in Rheumatoid Arthritis Patients Spur New Discovery
August 19, 2016
Rheumatoid arthritis patients taking medications that inhibit interleukin-1beta (IL-1beta), a molecule that stimulates the immune system, are 300 times more likely to experience invasive Group A Streptococcal infections than patients not on the drug, according to University of California San Diego School of Medicine researchers. Their study, published August 19…
UC San Diego’s Mark Herzik Named 2020 Searle Scholar
May 14, 2020
…to reveal new potential targets for therapeutics and avenues for structure-aided drug design. In addition, Herzik pioneered the development of novel strategies for collecting and processing high-resolution cryo-EM data, with particular emphasis toward imaging small (<200 kDa) macromolecules, as well as developing novel methodologies for validating atomic models generated against…
