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Your search for “Therapy Target” returned 457 results

Researchers Find Link Between Inflammation, Tissue Regeneration and Wound Repair Response

February 25, 2015

Writing in the February 25 online issue of Nature, an international team of scientists, headed by researchers at the University of California, San Diego School of Medicine, report finding new links between inflammation and regeneration: signaling pathways that are activated by a receptor protein called gp130.

Researchers Find New Genetic Links Underlying Progressively Blinding Eye Disease

March 30, 2017

Researchers at University of California San Diego School of Medicine, with colleagues at Case Western University, Duke University, the National Institutes of Health and elsewhere, have identified three novel genomic loci — distinct stretches of genetic material on chromosomes — linked to Fuchs endothelial corneal dystrophy (FECD), which often clusters…

When Strains of E.coli Play Rock-Paper-Scissors, It’s Not the Strongest That Survives

December 9, 2020

What happens when different strains of bacteria are present in the same system? Do they co-exist? Do the strongest survive? In a microbial game of rock-paper-scissors, researchers at the University of California San Diego’s BioCircuits Institute uncovered a surprising answer.

Synthetic Biology Used to Limit Bacterial Growth and Coordinate Drug Release

July 20, 2016

Researchers at the University of California San Diego and the Massachusetts Institute of Technology (MIT) have come up with a strategy for using synthetic biology in therapeutics. The team engineered a clinically relevant bacterium to produce cancer drugs and then self-destruct and release the drugs at the site of tumors.…

Study Helps Resolve Debate About How Tumors Spread

November 29, 2012

A team of scientists, led by researchers at the University of California, San Diego School of Medicine, has shown for the first time how cancer cells control the ON/OFF switch of a program used by developing embryos to effectively metastasize in vivo, breaking free and spreading to other parts of…

Two Studies Identify Potential New Drug for Crohn’s Disease and Ulcerative Colitis

August 21, 2013

Vedolizumab, a new intravenous antibody medication, has shown positive results for treating both Crohn’s disease and ulcerative colitis, according to researchers at the University of California San Diego, School of Medicine. The findings, published in two papers, will appear in the August 22 issue of the New England Journal of…

Enhancer RNAs Alter Gene Expression

June 3, 2013

In a pair of distinct but complementary papers, researchers at the University of California, San Diego School of Medicine and colleagues illuminate the functional importance of a relatively new class of RNA molecules. The work, published online this week in the journal Nature, suggests modulation of “enhancer-directed RNAs” or “eRNAs”…

First Angioedema Treatment Center Opens at UC San Diego Health System

November 24, 2014

UC San Diego Health System in partnership with the U.S. Hereditary Angioedema Association (HAEA), a non-profit patient advocacy organization, has opened the nation’s first dedicated center for diagnosing and treating diverse forms of swelling, known collectively as angioedema.

UC San Diego oneAPI Center of Excellence to Bring High-performance Simulations to Amber

September 23, 2022

The University of California San Diego announces establishing a new oneAPI Center of Excellence at its San Diego Supercomputer Center. The oneAPI Center will focus on enabling high-performance molecular dynamics simulations in Amber—a biomolecular simulations software package used by thousands.

A Father’s Journey from Stroke to Son’s Wedding

August 27, 2024

A stroke recovery at UC San Diego Health allowed a patient to attend his son’s wedding just days later, highlighting hope and exceptional stroke care.

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