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Your search for “Therapy Target” returned 457 results

Study: Two Enzymes Control Liver Damage in NASH

February 6, 2020

After identifying a molecular pathway that allows nonalcoholic steatohepatitis (NASH) to progress into liver cell death, University of California San Diego School of Medicine researchers were able to use these pathways to halt further liver damage.

UC San Diego Researchers Honored as Prebys Research Heroes

May 2, 2024

Stephanie Fraley, Marygorret Obonyo and Daniela Valdez-Jasso have been named Prebys Research Heroes. Grants totaling $1.5 million from the Prebys Foundation will support their research focused on advancing health care and medical discoveries.

Cancer Treatment of Tomorrow, Today

February 6, 2024

Moores Cancer Center continues to bring state-of-the-art cancer treatments from the bench to the bedside.

Selective, Toxin-Bearing Antibodies Could Help Treat Liver Fibrosis

July 12, 2021

UC San Diego researchers discovered that immunotoxins targeting the protein mesothelin prevent liver cells from producing collagen, a precursor to fibrosis and cirrhosis, in mouse models of human disease.

Using CRISPR to Reverse Retinitis Pigmentosa and Restore Visual Function

April 21, 2017

Using the gene-editing tool CRISPR/Cas9, researchers at University of California San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health, with colleagues in China, have reprogrammed mutated rod photoreceptors to become functioning cone photoreceptors, reversing cellular degeneration and restoring visual function in two mouse models of…

Therapeutic Potential of Bizarre ‘Jumbo’ Viruses Tapped for $10M HHMI Emerging Pathogens Project

January 26, 2023

UC San Diego and its collaborating partners have been awarded $10 million from the Howard Hughes Medical Institute to leverage the biomedical promise of viruses known as bacteriophages as new therapeutic agents in the fight against the rising crisis of antibiotic-resistant bacterial infections.

New Radiation Therapy Delays Brain Cancer Regrowth, Protects Healthy Tissue

September 19, 2022

UC San Diego Health now offers a novel therapy option shown to extend the lifespan and improve quality of life for certain patients.

Rock Tour “Text2Give” Supports Immunotherapy at UC San Diego Health

April 19, 2017

Rock star drummer Rikki Rockett feels very lucky to be on tour with his band, Poison. A year ago, he didn’t know if he would survive tongue cancer but after participating in an immunotherapy clinical trial at Moores Cancer Center at UC San Diego Health, he was declared cancer-free in…

Testing Antioxidant Drugs is Transparent

November 21, 2011

A study using genetically modified zebrafish to visualize early events involved in development of human atherosclerosis describes an efficient model – one that the researchers say offers many applications for testing the potential effectiveness of new antioxidant and dietary therapies.

Untangling Tau: Researchers Find a “Druggable Target” for Treating Alzheimer’s Disease

January 24, 2019

Using induced pluripotent stem cell-derived neurons from Alzheimer’s patients, UC San Diego researchers say cholesteryl esters — the storage product for excess cholesterol within cells — act as regulators of the protein tau, providing a new druggable target for the disease.

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