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Your search for “STEM” returned 869 results

Small Molecule Drug Reverses ADAR1-induced Cancer Stem Cell Cloning Capacity

February 16, 2023

UC San Diego researchers report that a late-stage, pre-clinical small molecule inhibitor reverses malignant hyper-editing by a protein that promotes silencing of the immune response, metastasis and therapeutic resistance in 20 different cancer types.

Phase I Trial Finds Experimental Drug Safe in Treating Chronic Lymphocytic Leukemia

June 1, 2018

…cirmtuzumab, an experimental monoclonal antibody-based drug, measurably inhibited the “stemness” of chronic lymphocytic leukemia cancer (CLL) cells — their ability to self-renew and resist terminal differentiation and senescence.

Recent Graduates Build Puzzle-Solving Robot to Engage Students in STEM Fields

December 23, 2014

Their robot won’t break the world record for solving Rubik’s Cube, but Daryl Stimm and William Mutterspaugh have an even more ambitious goal: using it to get thousands of girls and boys interested in science and technology.

UC San Diego is World’s 7th Best Public University, According to Times Higher Education

September 23, 2016

The University of California San Diego has been ranked the seventh best public university across the globe by Times Higher Education World University Rankings. In its 2016–17 report, the London-based publication ranked UC San Diego 22nd in the United States and 41st internationally.

UC San Diego Researchers Launch Combination Drug Trial to Eradicate B-Cell Malignancies

March 9, 2018

…grant from the state’s stem cell agency, researchers at University of California San Diego School of Medicine, in collaboration with local biotechnology company Oncternal Therapeutics, have launched a phase Ib/II clinical trial to evaluate the combined effectiveness of a standard of care drug with a novel monoclonal antibody that target…

Zika Virus May Cause Microcephaly by Hijacking Human Immune Molecule

May 6, 2016

…brain cells. The study, published May 6 in Cell Stem Cell, also shows that inhibiting this mechanism reduces brain cell damage, hinting at a new therapeutic approach to mitigating the effects of prenatal Zika virus infection.

Signaling Molecule Crucial to Stem Cell Reprogramming

November 20, 2014

While investigating a rare genetic disorder, researchers at the University of California, San Diego School of Medicine have discovered that a ubiquitous signaling molecule is crucial to cellular reprogramming, a finding with significant implications for stem cell-based regenerative medicine, wound repair therapies and potential cancer treatments.

Alice C. Tyler Perpetual Trust Gives $125,000 for Sally Ride Scholarship at UC San Diego

March 9, 2016

Scholarship, honoring late astronaut Sally Ride, will support students committed to protecting the planet

It’s Not a Rat’s Race for Human Stem Cells Grafted to Repair Spinal Cord Injuries

August 28, 2017

…Diego Veterans Administration Medical Center report that human neural stem cells (NSCs) grafted into spinal cord injuries in laboratory rats displayed continued growth and maturity, with functional recovery beginning one year after grafting.

‘Monster Tumors’ Could Offer New Glimpse at Human Development

November 4, 2020

Finding just the right model to study human development—from the early embryonic stage onward—has been a challenge for scientists over the last decade. Now, bioengineers at the University of California San Diego have homed in on an unusual candidate: teratomas.

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