May 25, 2012
Five scientists from the University of California, San Diego and its School of Medicine have been awarded almost $12 million in new grants from the California Institute for Regenerative Medicine (CIRM) to conduct stem cell-based research into regenerating spinal cord injuries, repairing gene mutations that cause amyotrophic lateral sclerosis and…
October 10, 2011
A newly developed method for microscopically extracting, or “mining,” information from genomes could represent a significant boost in the search for new therapeutic drugs and improve science’s understanding of basic functions such as how cells communicate with one another.
January 10, 2013
Repression of a single protein in ordinary fibroblasts is sufficient to directly convert the cells into functional neurons. The findings, which could have far-reaching implications for the development of new treatments for neurodegenerative diseases like Huntington’s, Parkinson’s and Alzheimer’s, will be published online in advance of the January 17 issue…
November 8, 2024
Researchers at UC San Diego identify a key pathway leading to neurodegeneration in early stages of ALS, hinting at the potential for short-circuiting the progression of the fatal disease if diagnosed early.
May 30, 2022
UC San Diego researchers discover mechanism linking breast cancer and diabetes, each of which promotes development and growth of the other.
August 3, 2020
UC San Diego researchers discovered that people with an inactive RNA-editing enzyme respond better to cancer immunotherapy, and inhibitors of the enzyme help mice with difficult-to-treat cancers live longer.
March 13, 2019
New preclinical data from University of California San Diego School of Medicine and Moores Cancer Center offers proof-of-principle for a combination immunotherapy that suppresses tumor growth in the liver. Current therapies for liver cancer are largely ineffective, resulting in poor outcomes.
May 5, 2022
…was injured, delivering specific therapeutics to treat the injury and improve the patient’s long-term quality of life. “It’s really a dire state for these patients, and TBI is unfortunately quite prevalent,” said Kwon. “Patients with a traumatic brain injury will often experience changes in their motor function, their cognitive abilities…
March 7, 2023
UC San Diego researchers delve deep into the unknown cause of pediatric acute myeloid leukemia to identify a gene splicing dysregulation and potential target for treating the disease, which often becomes treatment-resistant.
August 2, 2021
UC San Diego researchers modify remdesivir, creating oral version that can be taken earlier in COVID-19 diagnoses. In cell and animal studies, revised drug proved effective and safe.
