February 8, 2016
…– have nonalcoholic fatty liver disease (NAFLD), a chronic condition that can lead to cirrhosis, liver cancer and liver failure. Combining a diverse array of basic science, biomarkers, imaging and clinical efforts, University of California, San Diego School of Medicine has launched a new NAFLD Research Center to better understand…
May 2, 2017
Nonalcoholic fatty liver disease (NAFLD) — a condition that can lead to liver cirrhosis and cancer — isn’t typically detected until well advanced. Even then, diagnosis requires a biopsy. To more easily detect NAFLD, UC San Diego School of Medicine researchers and their collaborators report that the microbial makeup of…
August 25, 2020
UC San Diego researchers engineered fluorescent tools that combine the gene editing technique CRISPR and biosensor technologies to look inside cells in a whole new way. Their findings show that a major protein that binds to the signaling molecule cAMP can form membraneless organelles in human cells.
July 21, 2020
An international team of researchers has developed a non-invasive blood test that can detect whether an individual has one of five common types of cancers, four years before the condition can be diagnosed with current methods.
August 6, 2012
Researchers at the University of California, San Diego School of Medicine say neutrophils, an abundant type of white blood cell typically tasked with attacking bacteria and other foreign invaders, also plays an unexpected role in mediating insulin resistance – the central characteristic of type 2 diabetes, which afflicts an estimated…
August 24, 2020
Researchers at University of California San Diego School of Medicine report that fructose only adversely affects the liver after it reaches the intestines, where the sugar disrupts the epithelial barrier protecting internal organs from bacterial toxins in the gut.
June 16, 2020
A first-in-class clinical trial suggests a novel treatment measurably slowed progression of non-alcoholic fatty liver disease to its more progressive and deadly form.
July 6, 2015
Using human tumor samples and mouse models, researchers at University of California, San Diego School of Medicine and Moores Cancer Center discovered that cancer stem cell properties are determined by epigenetic changes — chemical modifications cells use to control which genes are turned on or off.
August 5, 2013
…could substantially increase colorectal cancer screening among uninsured patients, a study published in the August 5 online edition of JAMA Internal Medicine reveals. The research also suggests that a non-invasive colorectal screening approach, such as a fecal immunochemical test might be more effective in promoting participation in potentially life-saving colon…
February 10, 2020
UC San Diego researchers use 3D human gut organoids to reveal the molecular system that keeps intestinal linings sealed, demonstrate how the system breaks down and how it can be strengthened with the diabetes drug metformin.
