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Your search for “Lung Infections” returned 83 results

Pair of Discoveries Illuminate New Paths to Flu and Anthrax Treatments

October 17, 2017

Two recent studies led by UC San Diego biologists have set the research groundwork for new avenues to treat influenza and anthrax poisoning. Published in PLOS Pathogens, the studies from Professor Ethan Bier’s laboratory used a series of experiments to identify key pathways and mechanisms previously unknown or overlooked in…

Newly Identified Target May Help with Drug Discovery for Chronic Inflammatory Diseases

July 25, 2018

In a study published online July 25 in the journal Nature, University of California San Diego School of Medicine researchers identified a signaling pathway that activates the NLRP3 inflammasome implicated in several severe chronic inflammatory disorders.

Rethinking Remdesivir

August 2, 2021

UC San Diego researchers modify remdesivir, creating oral version that can be taken earlier in COVID-19 diagnoses. In cell and animal studies, revised drug proved effective and safe.

E-Cigarette Vapor Boosts Superbugs and Dampens Immune System

January 26, 2016

Researchers at the University of California, San Diego School of Medicine and Veterans Affairs San Diego Healthcare System report data suggesting that e-cigarettes are toxic to human airway cells, suppress immune defenses and alter inflammation, while at the same time boosting bacterial virulence. The mouse study is published January 25…

What Elephant Seals Can Tell Us About Using Carbon Monoxide to Heal

April 4, 2016

In a new study, most marine mammals were found to exhale carbon monoxide at levels equivalent to or greater than the amount exhaled by a several-packs-a-day smoker.

Nanosponges Could Intercept Coronavirus Infection

June 17, 2020

Nanoparticles cloaked in human lung cell membranes and human immune cell membranes can attract and neutralize the SARS-CoV-2 virus in cell culture, causing the virus to lose its ability to hijack host cells and reproduce.

Statins Reduce COVID-19 Severity, Likely by Removing Cholesterol That Virus Uses to Infect

September 23, 2020

Analyzing anonymized patient medical records, UC San Diego researchers discovered that cholesterol-lowering statins reduced risk of severe COVID-19 infection, while lab experiments uncovered a cellular mechanism that helps explain why.

Computational Models Move Researchers Closer to Tuberculosis Vaccine

January 13, 2022

According to a 2021 World Health Organization report, the global COVID-19 pandemic caused an increase in tuberculosis (TB) deaths – 1.5 million in 2020 versus 1.4 million in 2019 – due to a lack of efficient diagnosis and treatment.

UC San Diego Health Joins International Clinical Trial to Test Coronavirus Vaccine

October 1, 2020

UC San Diego Health will be a test site for a third, major Phase III clinical trial to assess a vaccine candidate for the novel coronavirus that causes COVID-19. Sponsored by Janssen Pharmaceuticals, the trial will recruit up to 60,000 participants at sites in the United States and worldwide.

Researchers Find a Likely Cause of Inflammatory Myofibroblastic Tumors

June 27, 2016

Researchers at University of California San Diego School of Medicine have found that a likely cause of inflammatory myofibroblastic tumors is deficiency in nonsense-mediated RNA decay (NMD), a system cells use to control which genes are activated.

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