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Your search for “Inflammation” returned 378 results

Starving Inflammatory Immune Cells Slows Damage Caused by Multiple Sclerosis

September 1, 2011

In a paper published today in the journal Scientific Reports, a pair of researchers at the University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences report that inhibiting the ability of immune cells to use fatty acids as fuel measurably slows disease progression in a mouse model…

Diet Plays Critical Role in NASH Progressing to Liver Cancer in Mouse Model

June 1, 2021

Researchers at University of California San Diego School of Medicine found in a mouse model that when fed a Western diet rich in calories, fat and cholesterol, the mice progressively became obese, diabetic and developed NASH, which progressed to HCC, chronic kidney and cardiovascular disease.

Nuclei-free Cells Prove Utility in Delivering Therapeutics to Diseased Tissues

January 14, 2022

UC San Diego researchers report successfully removing the nucleus from a type of ubiquitous cell, then using the genetically engineered cell as a unique cargo-carrier to deliver therapeutics precisely to diseased tissues.Researchers at University of California San Diego School of Medicine and Moores

Two Anti-viral Enzymes Transform Pre-Leukemia Stem Cells into Leukemia

January 26, 2021

Viral infections and space travel similarly trigger inflammation and the enzymes APOBEC3C and ADAR1; UC San Diego researchers are developing ways to inhibit them as a means to potentially lower cancer risk for both astronauts and people on Earth.

Nuisance Seaweed Found to Produce Compounds with Biomedical Potential

May 24, 2012

A seaweed considered a threat to the healthy growth of coral reefs in Hawaii may possess the ability to produce substances that could one day treat human diseases, a new study led by scientists at Scripps Institution of Oceanography at UC San Diego has revealed.

UC San Diego Part of New Effort to Fight Autoimmune Disorders

September 25, 2014

The Division of Rheumatology, Allergy and Immunology at University of California, San Diego School of Medicine has been named a key site in a national, multi-institution, multi-year $41.6 million program to speed drug discovery, development, diagnostics and therapies for patients with autoimmune disorders, primarily rheumatoid arthritis (RA) and lupus erythematosus,…

Evolutionary Gene Loss May Help Explain Why Only Humans are Prone to Heart Attacks

July 22, 2019

University of California San Diego School of Medicine scientists say the loss of a single gene two to three million years ago in our ancestors may have resulted in a heightened risk of cardiovascular disease in all humans as a species, while also setting up a further risk for red…

Before There Will Be Blood

November 6, 2014

Researchers at the University of California, San Diego School of Medicine describe the surprising and crucial involvement of a pro-inflammatory signaling protein in the creation of hematopoietic stem cells (HSCs) during embryonic development, a finding that could help scientists to finally reproduce HSCs for therapeutic use.

Post-COVID Lung Disease Shares Origins with Other Scarring Lung Disorders

July 20, 2022

UC San Diego researchers provide first insights into the fundamental cellular pathologies that drive interstitial lung disease in patients post-COVID.

Neurons Stripped of Their Identity Are Hallmark of Alzheimer’s Disease, Study Finds

November 13, 2020

UC San Diego researchers have identified new mechanisms in neurons that cause Alzheimer’s disease. In particular, they discovered that structural changes in chromatin trigger neurons to lose their specialized function and revert to a precursor-like state.

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