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Your search for “Immune System” returned 447 results

Experimental Therapy for Parasitic Heart Disease May Also Help Stop COVID-19

April 2, 2021

UC San Diego researchers found that the chemical inhibitor K777 reduces the coronavirus’ ability to infect cell lines by blocking human enzyme cathepsin L; clinical trials are underway.

Researchers Map Druggable Genomic Targets in Evolving Malaria Parasite

January 11, 2018

Researchers at University of California San Diego School of Medicine, with colleagues across the country and around the world, have used whole genome analyses and chemogenetics to identify new drug targets and resistance genes in 262 parasite cell lines of Plasmodium falciparum — protozoan pathogens that cause malaria — that…

How Well do COVID-19 Vaccines Work Over the Longer Term?

April 1, 2021

UC San Diego students will participate in nationwide clinical trial to assess if COVID-19 vaccination prevents infection and reduces risk of transmission.

Sugar-Coating Disguise Allows for Coronavirus Infection

June 18, 2020

…glycans, tricks the human immune system into identifying the microbe as harmless. The resulting recognition failure keeps the body from generating the defensive antibodies needed to destroy the invading coronavirus. Rommie Amaro, professor of chemistry and biochemistry, UC San Diego Using the National Science Foundation-funded Frontera supercomputer at the Texas…

Adding MS Drug to Targeted Cancer Therapy May Improve Glioblastoma Outcomes

August 8, 2019

The multiple sclerosis drug teriflunomide, paired with targeted cancer therapy, markedly shrinks patient-derived glioblastomas grown in mice by reaching stem cells at the tumor’s root, according to a new UC San Diego School of Medicine study published in Science Translational Medicine.

UC San Diego Researchers Help Discover That Tiny DNA Circles are Key Drivers of Cancer

April 12, 2023

University of California San Diego computer scientists are among the lead authors of an international study that finds tiny circles of DNA that defy the accepted laws of genetics are key drivers of cancer formation.

Zika Virus Targets and Kills Brain Cancer Stem Cells

September 5, 2017

In developing fetuses, infection by the Zika virus can result in devastating neurological damage, most notably microcephaly and other brain malformations. In a new study, published today in The Journal of Experimental Medicine, researchers at the University of California San Diego School of Medicine and Washington University School of Medicine…

Charting Shots

October 7, 2021

…that triggered a similar immune response. The cartoon was intended to both lampoon the most extreme anti-vaccination efforts and to illustrate ongoing social anxieties. Charting Shots The history of vaccines, including hesitancy, is pointedly and painfully familiar Many medical advances lay at least partial claim to greatest of all time,…

Renowned UC San Diego Microbiome Pioneer Rob Knight Elected to the National Academy of Engineering

February 7, 2024

Rob Knight, a University of California San Diego professor and international leader in the study of the roles microbes play in human health and disease and the functioning of ecosystems, has been elected to the National Academy of Engineering.

This Injectable Hydrogel Mitigates Damage to the Right Ventricle of the Heart

March 6, 2024

An injectable hydrogel can mitigate damage to the right ventricle of the heart with chronic pressure overload, according to a new study published March 6 in Journals of the American College of Cardiology: Basic to Translational Science.

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