March 24, 2016
…24 online issue of The American Journal of Human Genetics. The findings, they say, represent a significant advance in efforts to unravel the genetic basis of autism spectrum disorder (ASD).
February 13, 2020
…screened for dozens of genetic and congenital disorders, such as phenylketonuria (PKU), an inherited metabolic disorder that can result in intellectual disability, seizures, heart and behavioral problems. Researchers at University of California San Diego School of Medicine have launched a phase II research study to look for signs of another…
January 14, 2022
Using CRISPR/Cas9 technology, scientists have genetically engineered a method to reverse insecticide resistance. The gene replacement method offers a new way to fight deadly malaria spread and reduce the use of pesticides that protect valuable food crops.
May 9, 2019
Using stem cells derived from six people, UC San Diego School of Medicine researchers recapitulated retinal cells in the lab. This “eye-in-a-dish” model allowed them to identify genetic variants that cause age-related macular degeneration, a common cause of vision loss.
July 27, 2020
Researchers at Ludwig Institute for Cancer Research and University of California San Diego School of Medicine report that inhibiting a key enzyme caused human cancer cells associated with two major types of breast and ovarian cancer to die and in mouse studies reduced tumor growth.
December 19, 2013
Researchers at the University of California, San Diego School of Medicine, with colleagues in The Netherlands and United Kingdom, have produced the first map detailing the network of genetic interactions underlying the cellular response to ultraviolet (UV) radiation.
September 21, 2015
Albert La Spada, MD, PhD, professor of pediatrics, cellular and molecular medicine and neurosciences at University of California, San Diego School of Medicine, has received a 2015 Harrington Scholar award to advance his work on a therapy for Spinocerebellar ataxia type 7 (SCA7), a rare but devastating neurological disorder that…
February 9, 2017
Researchers at University of California San Diego School of Medicine, with colleagues at Rady Children’s Institute for Genomic Medicine and in London and Singapore, have conducted novel whole genome sequencing of a family in which two of four children were affected by Kawasaki disease. They have identified plausible gene variants…
December 11, 2017
Researchers at University of California San Diego School of Medicine have found a genetic signature for delay discounting — the tendency to undervalue future rewards — that overlaps with attention-deficit/hyperactivity disorder (ADHD), smoking and weight.
July 29, 2019
A genome-wide association study of more than 165,000 U.S. veterans confirms a genetic vulnerability to post-traumatic stress disorder, specifically noting abnormalities in stress hormone response and/or functioning of specific brain regions.
