April 9, 2015
Burrowing mice and how such animal behavior can shed light on the genetics of human behavior will be the subject of the 10th Richard H. and Glenda G. Rosenblatt Lectureship in Evolutionary Biology at Scripps Institution of Oceanography, UC San Diego.
February 6, 2018
Employing CRISPR/Cas9 advancements, UC San Diego researchers are using new active genetics technology to reveal new fundamental mechanisms that control gene activity. The authors also provide experimental validation for using active genetics as an efficient means for targeted gene insertion, or “transgenesis,” and single-step replacement of genetic control elements.
November 22, 2016
Genetic variations that increase schizophrenia risk are rare, making it difficult to study their role. To overcome this, the Psychiatric Genomics Consortium, an international team led by Jonathan Sebat, PhD, at University of California San Diego School of Medicine, analyzed the genomes of more than 41,000 people in the largest…
December 8, 2016
…Medicine in this week’s advance online publication of Nature Genetics. The findings also show correlations with psychiatric disorders.
October 11, 2013
…of the National Institutes of Health, to elucidate the genetics of glaucoma in persons of African descent.
January 23, 2019
Using active genetics technology, biologists have developed the world’s first CRISPR/Cas9-based approach to control genetic inheritance in a mammal. The achievement in mice lays the groundwork for further advances based on this technology, including biomedical research on human disease.
September 30, 2019
A small genetic study, published September 30, 2019 in Nature Genetics, identified a protein linked to many genetic variants that affect heart function. Researchers are expanding the model to other organ systems and at larger scales to create a broader understanding of genes and proteins involved.
September 20, 2016
…that risk for feeling lonely is partially due to genetics, but environment plays a bigger role.
September 10, 2015
Scientists at the University of California, San Diego School of Medicine have elucidated a genetic interaction that may prove key to the development and progression of glaucoma, a blinding neurodegenerative disease that affects tens of millions of people worldwide and is a leading cause of irreversible blindness.
October 31, 2022
Researchers at UC San Diego report that a polygenic hazard score based on 290 genetic variants could be an effective tool for predicting genetic risk of lethal prostate cancer, which kills more than 34,000 men in the U.S. annually.