November 22, 2016
…overcome this, the Psychiatric Genomics Consortium, an international team led by Jonathan Sebat, PhD, at University of California San Diego School of Medicine, analyzed the genomes of more than 41,000 people in the largest study of its kind to date. Their study, published November 21 in Nature Genetics, reveals regions…
March 4, 2022
An international team led by computer scientists at UC San Diego has shown that a new genome assembly algorithm can vastly improve large genomes reconstruction, the process by which DNA snippets are arranged into complete genomes, which is an essential aspect of genomic sequencing.
August 16, 2023
In a paper published this week in the journal Nature Methods, UC San Diego researchers shared a new UniAligner algorithm for comparing highly repetitive genomic regions.
September 18, 2013
Sequencing the DNA of an organism, whether human, plant, or jellyfish, has become a straightforward task, but assembling the information gathered into something coherent remains a massive data challenge.
March 10, 2023
A study led by Assistant Professor Emma Farley and two graduate students has found that developing genomes not only follow a precise pattern of expression, but the process is governed by rules that are similar to the ways in which grammar systematically structures our languages.
June 6, 2016
…researchers examined the Staph “pan-genome” — the genomes of 64 different strains that differ in where they live, the types of hosts they infect and their antibiotic resistance profiles. This effort, published June 6 by PNAS, places all Staph genes into one of two categories: the core genome or the…
February 6, 2024
UC San Diego scientists have shown that they can now predict which single-letter changes to the DNA within our genomes will alter genetic instructions and disrupt development, leading to changes such as the growth of extra digits and hearts.
February 16, 2016
An international team of computer scientists developed a method that greatly improves researchers’ ability to sequence the DNA of organisms that can’t be cultured in the lab, such as microbes living in the human gut or bacteria living in the depths of the ocean. They published their work in the…
September 7, 2023
Researchers turned to a descendant variety of Hass—the world’s most popular avocado—to explore the fruit’s evolutionary history through its genome.
November 12, 2013
…of California, San Diego have generated the most complete genome sequences from single E. coli cells and individual neurons from the human brain. The breakthrough comes from a new single-cell genome sequencing technique that confines genome amplification to fluid-filled wells with a volume of just 12 nanoliters.
