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Your search for “Drug Discovery” returned 426 results

Researchers ID Natural Products with Potential Efficacy Against Coronavirus, Other Lethal Viruses

January 5, 2021

Researchers describe the biology of three families of RNA viruses including Coronavirus, Ebola, and Zika and the natural products that have been shown to have capabilities to inhibit them. The review provides a guide that could accelerate drug discovery in response to future epidemics.

Supercomputers Simulate New Pathways for Potential RNA Virus Treatment

December 17, 2020

New simulations done on supercomputers may help researchers understand how these inhibitors react and potentially help to develop a new generation of drugs to target viruses with high death rates including SARS-CoV2, the virus that causes COVID-19.

Biologists Discover Source for Boosting Tumor Cell Drug Sensitivity

October 29, 2018

…new way of re-sensitizing drug-resistant human tumor cells to the potency of DNA-damaging agents, the most widely used group of cancer drugs. In a new study, they describe how a human gene known as Schlafen 11 controls the sensitivity of tumor cells to DDAs. Their research may pave the way…

Biologists Develop Method for Antibiotic Susceptibility Testing

January 22, 2016

…hours, an advance that could slow the appearance of drug resistance and allow doctors to more rapidly identify the appropriate treatment for patients with life threatening bacterial infections.

AI Harnesses Tumor Genetics to Predict Treatment Response

January 18, 2024

Cancer resists treatment in a multitude of ways, but a new algorithm developed by scientists at UC San Diego can decode them all simultaneously.

Opioid Dependence Found to Permanently Change Brains of Rats

January 24, 2020

Approximately one-quarter of patients who are prescribed opioids for chronic pain misuse them, with five to 10 percent developing an opioid use disorder or addiction. In a new study, UC San Diego researchers found that opioid dependence produced permanent changes in the brains of rats.

Researchers Reveal 3D Structure of Cell’s Inflammation Sensor and its Inhibitors

December 7, 2016

…together may better enable pharmaceutical companies to develop anti-inflammatory drugs that bind and inhibit CCR2 in a similar manner. The study is published December 7 by Nature.

Researchers Develop New Strategy to Target KRAS Mutant Cancer

September 13, 2017

In a new study, published this month in Cancer Discovery, University of California San Diego School of Medicine researchers report that approximately half of lung and pancreatic cancers that originate with a KRAS mutation become addicted to the gene as they progress.

Golf Tournament Supports Cancer Research in Honor of Brian Schultz Aug 2

July 17, 2014

Golfers will gather on the green to honor their friend and fellow avid golfer Brian Schultz, who lost a sudden and brief battle with cancer at the age of 27. The 19th annual Brian Schultz Memorial Golf Classic will be held on Saturday, August 2 at the Rancho Bernardo Inn…

Leukemia Drug Shows Promise for Treating a Childhood Brain Cancer

September 20, 2019

Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego researchers describe new use of leukemia drug, nilotinib, to treat subtype of medulloblastoma, a deadly pediatric brain cancer.

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