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Your search for “Drug Discovery” returned 431 results

Roche Funds Drug Discovery Projects at UC San Diego

January 9, 2012

The new UC San Diego-Roche Extending Innovation Network (EIN) program has been launched with selection of its first three research projects at the University of California, San Diego School of Medicine.

Drug Discovery Potential of Natural Microbial Genomes

January 22, 2014

Scientists at the University of California, San Diego have developed a new genetic platform that allows efficient production of naturally occurring molecules, and have used it to produce a novel antibiotic compound. Their study, published this week in PNAS, may open new avenues for natural product discoveries and drug development.

UC San Diego Biophysicists Examine Development of Antibiotic Resistance

December 5, 2013

…antibiotics and developing new drugs against bacteria already resistant to conventional drug treatments. But understanding how bacteria grow and evolve drug resistance could also help stop its spread by allowing scientists to target the process of evolution itself. “Understanding how bacteria harboring antibiotic resistance grow in the presence of antibiotics…

Simulated Chemistry: New AI Platform Designs Tomorrow’s Cancer Drugs

May 6, 2024

Researchers from University of California San Diego have developed a new AI tool to that generate new drug candidates for cancer, which could help streamline the typically laborious drug discovery process.

Artificial Intelligence Aids Discovery of Super Tight-Binding Antibodies

January 31, 2023

UC San Diego scientists developed an artificial intelligence tool that could accelerate the development of new high affinity antibody drugs.

Cancer Drug and Antidepressants Provide Clues for Treating Fatal Brain-Eating Amoeba Infections

September 13, 2018

…identified three new molecular drug targets in Naegleria fowleri and a number of drugs that are able to inhibit the amoeba’s growth in a laboratory dish. Several of these drugs are already approved by the U.S. Food and Drug Administration for other uses, such as antifungal agents, the breast cancer…

New Way to Target – And Kill – Proliferating Tumors

November 14, 2011

…have identified a new drug discovery approach enabling the destruction of the most highly proliferative tumors. The discovery, published in the November 13 online issue of the journal Nature Medicine, points to an effective, alternative method for killing fast-growing cancer cells without causing some of the negative effects of current…

Clinical Trial Evaluates Synthetic Cannabinoid as Brain Cancer Treatment

September 25, 2012

Researchers at University of California, San Diego Moores Cancer Center are evaluating the safety and tolerability of a synthetic cannabinoid called dexanabinol (ETS2101). Delivered as a weekly intravenous infusion, the drug is being tested in patients with all forms of brain cancer, both primary and metastatic.

Pharmaceutical Companies to Share Data for Drug Design via New UC San Diego-Led Resource

October 9, 2014

…unreleased proprietary data for drug discovery through a new $3.7 million effort funded by the National Institutes for Health. The project, which is led by UC San Diego principal investigators Rommie Amaro, Victoria Feher and Dr. Michael K. Gilson, includes a major subcontract to Rutgers University, directed by Dr. Stephen…

Discovery Provides Blueprint for New Drugs That Can Inhibit Hepatitis C Virus

March 19, 2012

Chemists at the University of California, San Diego have produced the first high resolution structure of a molecule that when attached to the genetic material of the hepatitis C virus prevents it from reproducing. Hepatitis C is a chronic infectious disease that affects some 170 million people worldwide and causes…

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