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Your search for “Dementia” returned 130 results

Plaque Deposits Alone Do Not Trigger Clinical Symptoms of Alzheimer’s, Researchers Find

April 23, 2012

According to a new study, the neuron-killing pathology of Alzheimer’s disease (AD), which begins before clinical symptoms appear, requires the presence of both amyloid-beta (a-beta) plaque deposits and elevated levels of an altered protein called p-tau.

Genetics Overlap Found Between Alzheimer’s Disease and Cardiovascular Risk Factors

April 16, 2015

An international team of scientists, led by researchers at University of California, San Diego School of Medicine, have found genetic overlap between Alzheimer’s disease (AD) and two significant cardiovascular disease risk factors: high levels of inflammatory C-reactive protein (CRP) and plasma lipids or fats. The findings suggest the two cardiovascular…

SDSC Resources, Expertise Used in Genomic Analysis of 115 Year-Old Woman

April 29, 2014

A team of researchers investigating the genome of a healthy supercentenarian since 2011 has found many somatic mutations – permanent changes in cells other than reproductive ones – that arose during the woman’s lifetime. Led by Erik Sistermans and Henne Holstege from the VU University Medical Center in Amsterdam, the…

Engineering Students, Faculty at UC San Diego Remember Beloved Educator

September 12, 2016

A longtime favorite of students, faculty and administrators alike, former University of California San Diego electrical and computer engineering professor Anthony V. Sebald passed away on July 11, 2016. He was 74 years old. For nearly 30 years, Sebald served the campus, the Jacobs School of Engineering and its Department…

Reimagining Public Health

February 2, 2023

From pandemics to health inequities, confronting future crises will look different — and that’s a good thing.

Polygenic Risk Score May Identify Alzheimer’s Risk in Younger Populations

March 5, 2018

For the first time, an international team of scientists, led by researchers at University of California San Diego School of Medicine, have determined that an Alzheimer’s disease (AD) polygenic risk score can be used to correctly identify adults with mild cognitive impairment (MCI) who were only in their 50s. MCI…

Novel Treatment Approach to Alzheimer’s Disease Uses Vitamin B1 Derivative

July 19, 2022

With a $45 million grant from the NIH, UC San Diego researchers and collaborators will launch a nationwide clinical trial to further investigate the therapeutic potential of benfotiamine, a synthetic version of thiamine (B1), as a treatment for Alzheimer’s disease.

Eyes Provide Peek at Alzheimer’s Disease Risk

August 23, 2021

Amyloid plaques found in the retinas of eyes may be an indicator of similar plaques in the brain, a hallmark of Alzheimer’s disease, and may provide a more visible biomarker for detecting disease risk.

Neurobiologists Reveal How Value Decisions are Coded into Our Brains

November 23, 2021

A new study is showing how value choices are recorded in our brains. Researchers found that persistency allows value signals to be most effectively represented, or “coded,” across different areas of the brain, especially in a critical area within the cerebrum known as the retrosplenial cortex.

Walkable Neighborhoods Help Adults Socialize, Increase Community

June 20, 2023

Adults who live in walkable neighborhoods are more likely to socialize and have a stronger sense of community, report researchers at the UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science.

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