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Your search for “Dementia” returned 125 results

Withdrawal from Psychostimulants Restructures Functional Architecture of Brain

September 27, 2021

Researchers describe how withdrawal from nicotine, methamphetamine and cocaine alters the functional architecture and patterns in the brains of mice, compared to control animals, a key to developing addiction treatments.

In Life and Death, Alzheimer’s Disease Looks Different among Hispanic Patients

January 24, 2019

Researchers at University of California San Diego School of Medicine report that autopsies of patients diagnosed with Alzheimer’s disease when they were alive — and confirmed by autopsy — indicate many cognitive issues symptomatic of the condition are less noticeable in living Hispanic patients.

A “Frenemy” in Parkinson’s Disease Takes to Crowdsourcing

September 29, 2014

Researchers have found that a key neuronal protein called alpha-synuclein normally gathers in synapses, where aggregates of it help regulate neurotransmissions. In overabundance, though, a-synuclein can choke off communication altogether, leading to neuronal death and related diseases.

First-in-Human Clinical Trial to Assess Gene Therapy for Alzheimer’s Disease

February 18, 2021

UC San Diego researchers have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer’s disease or Mild Cognitive Impairment, a condition that often precedes full-blown dementia.

Commonly Used Drugs for Schizophrenia Linked to Greater Cognitive Impairment

May 17, 2021

UC San Diego researchers report that medications commonly prescribed to reduce the severity of physical and mental health symptoms associated with schizophrenia may have a cumulative effect of worsening cognitive function in patients.

Small Loop in Human Prion Protein Prevents Chronic Wasting Disease

February 23, 2015

Chronic wasting disease (CWD) affects North American elk and deer, but has not been observed in humans. Using a mouse model that expresses an altered form of the normal human prion protein, researchers at University of California, San Diego School of Medicine have determined why the human proteins aren’t corrupted…

Three UC San Diego Researchers Receive New CIRM Grants

March 19, 2013

Researchers at the University of California, San Diego School of Medicine are principal investigators in two of nine new grants approved today by the governing board of the California Institute for Regenerative Medicine (CIRM).

Plaque Deposits Alone Do Not Trigger Clinical Symptoms of Alzheimer’s, Researchers Find

April 23, 2012

According to a new study, the neuron-killing pathology of Alzheimer’s disease (AD), which begins before clinical symptoms appear, requires the presence of both amyloid-beta (a-beta) plaque deposits and elevated levels of an altered protein called p-tau.

Happiness in Schizophrenia

August 18, 2014

Schizophrenia is among the most severe forms of mental illness, yet some people with the disease are as happy as those in good physical and mental health according to a study led by researchers at the University of California, San Diego School of Medicine.

Genetics Overlap Found Between Alzheimer’s Disease and Cardiovascular Risk Factors

April 16, 2015

An international team of scientists, led by researchers at University of California, San Diego School of Medicine, have found genetic overlap between Alzheimer’s disease (AD) and two significant cardiovascular disease risk factors: high levels of inflammatory C-reactive protein (CRP) and plasma lipids or fats. The findings suggest the two cardiovascular…

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