March 13, 2020
UC San Diego researchers discover the enzyme SPRK1’s role in reorganizing the paternal genome during the first moments of fertilization — a finding that might help explain infertility cases of unknown cause.
October 2, 2016
Approximately 20 percent of all human cancers have mutations in a gene called KRAS. KRAS-mutant cancers are among the most difficult to treat, with poor survival and resistance to chemotherapy. Researchers at University of California San Diego School of Medicine and Moores Cancer Center used microRNAs to systematically inhibit thousands…
April 16, 2014
Spinal and bulbar muscular atrophy (SBMA) is a rare inherited neuromuscular disorder characterized by slowly progressive muscle weakness and atrophy. In a new study published in the online issue of Neuron, a team of scientists at the University of California, San Diego School of Medicine say novel mouse studies indicate…
March 26, 2024
While CRISPR has shown immense promise as a next-generation therapeutic tool, the gene editing technology’s edits are still imperfect. Researchers have developed a new genetic system to test and analyze CRISPR-based DNA repair and related risks from unintended but harmful “bystander” edits.
April 2, 2015
…stem cells open slowly over time, in the same sequence that occurs during embryonic development. It isn’t until certain chromosomal regions have acquired the “open” state that they are able to respond and become liver or pancreatic cells.
February 13, 2014
…human beings are essentially “DNA-driven software machines.” As such, we are each merely a collective mass of genomic data which, when unraveled, holds the promise of answering the age-old question of “What is life?” “The reality is the reality,” said Venter, who spoke recently at UC San Diego. “Every life…
June 24, 2020
UC San Diego researchers have discovered that a single treatment to inhibit a gene called PTB in mice converts native astrocytes, brain support cells, into neurons that produce the neurotransmitter dopamine. As a result, the mice’s Parkinson’s disease symptoms disappear.
August 9, 2017
Microbiome researchers Rob Knight, PhD, University of California San Diego, Jeffrey Gordon, MD, Washington University School of Medicine in St. Louis, and Norman Pace, PhD, University of Colorado Boulder, will share this year’s Massry Prize, splitting the $200,000 honorarium. These researchers lead a field that works to produce a detailed…
April 23, 2014
Two UC San Diego faculty members have been elected to the American Academy of Arts and Sciences, one of the nation’s most prestigious honorary societies, which includes accomplished leaders from academe, business, public affairs, the humanities and the arts.
February 7, 2020
The Protein Data Bank archive has released a new Coronavirus protease structure following the recent coronavirus outbreak, an ongoing viral epidemic primarily affecting mainland China that now threatens to spread to other parts of the world.
