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Your search for “Cellular Pathways” returned 184 results

Popular Pharmaceutical Target in Cells May Prove Even More Useful

October 26, 2022

Researchers at UC San Diego have identified a new signaling process involving G protein-coupled receptors (GPCRs), a cellular target already exploited by hundreds of diverse drugs. The discovery opens the possibility of new therapies, including for multiple forms of cancer.

Noted Researcher and Scientific Leader Jack E. Dixon Retires

May 27, 2021

Jack E. Dixon, whose distinguished and varied 48-year career ranged from helping reveal how cells communicate to becoming a renowned scientific leader at UC San Diego School of Medicine and Howard Hughes Medical Institute, is retiring.

Researchers Illuminate Key Role of NOX Proteins in Liver Disease

July 29, 2015

Researchers at the University of California, San Diego School of Medicine have demonstrated a direct connection between two signaling proteins and liver fibrosis, a scarring process underlying chronic liver disease, the 12th leading cause of death in the United States.

Three UC San Diego Professors Elected to National Academy of Sciences

May 2, 2019

The National Academy of Sciences announced that Susan Ackerman and Bill McGinnis have been elected to membership in the prestigious organization, one of the highest honors for U.S. scientists. Also elected this year is Jeremy Jackson, professor emeritus with Scripps Institution of Oceanography.

Tumor Reasons Why Cancers Thrive in Chromosomal Chaos

October 26, 2021

University of California San Diego researchers describe how a pair of fundamental genetic and cellular processes — aneuploidy and unfolded protein response — are exploited by cancer cells to promote tumor survival and growth.

Of Mice, Not Men

November 19, 2014

Researchers at the University of California, San Diego School of Medicine and Ludwig Cancer Research, with colleagues across the country and world, have discovered that a significant number of mouse genes do not in fact behave like their human counterparts, suggesting science will need to rethink at least some roles…

Organoids Reveal Similarities Between Myotonic Dystrophy Type 1 and Rett Syndrome

June 29, 2022

Using brain organoids, UC San Diego researchers discover mutational commonalities between muscular dystrophy type 1 and Rett syndrome, suggesting the potential of a similar treatment for both.

Community Embraces Effort to Build 3D Virtual Cell

January 2, 2013

Scientists from the University of California, San Diego, national and international research centers launched a first-of-its-kind workshop series intended to bring together investigators from a wide range of scientific fields to develop a 3D Virtual Cell. Funding for the Dec. 13-14 conference was provided by the National Science Foundation (NSF).

Joint Resolution: A Link Between Huntington’s Disease and Rheumatoid Arthritis

May 15, 2018

Using new analytic tools, researchers at University of California San Diego School of Medicine and the Icahn School of Medicine at Mount Sinai have decoded the epigenetic landscape for rheumatoid arthritis (RA), a common autoimmune disease that affects more than 1.3 million Americans.

Blood Testing Identifies Biomarkers of Suicidal Thoughts

December 15, 2023

Researchers from University of California San Diego have found that people with depression and suicidal ideation have compounds in their blood that could help identify people at higher risk of becoming suicidal. They also found sex-based differences in how depression impacts metabolism.

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