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Your search for “Cancer Research” returned 1389 results

Drug Suppresses Spread of Breast Cancer Caused by Stem-like Cells

December 11, 2017

…play a critical role in the spread of breast cancer, but a vulnerability in the pathway that powers them offers a strategy to target these cells using existing drugs before metastatic disease occurs, report University of California San Diego School of Medicine and Moores Cancer Center researchers.

Stress-Tolerant Cells Drive Tumor Initiation in Pancreatic Cancer

January 17, 2023

UC San Diego scientists discover a molecular pathway critical to the initiation of pancreatic tumors. The findings may inspire new chemotherapeutic drugs targeting early stages of tumor formation and spread

UC San Diego Engineers Inducted Into 2024 Class of the AIMBE College of Fellows

March 25, 2024

Engineering professors Ludmil Alexandrov and Sheng Xu were inducted into the College of Fellows of the American Institute for Medical and Biological Engineering (AIMBE), one of the highest distinctions accorded to medical and biological engineers.

Potential Drug Target for Difficult-To-Treat Breast Cancer: RNA-Binding Proteins

July 2, 2021

UC San Diego studies using human cell lines and tumors grown in mice provide early evidence that inhibiting RNA-binding proteins, a previously overlooked family of molecules, might provide a new approach for treating some cancers.

Stem Cell-Derived Therapy Shows Promise Against Treatment-Resistant Liver Cancer

July 9, 2024

Discover research from UC San Diego showing how stem cell-derived therapy, targeting treatment-resistant liver cancer through genetically modified NK cells, offers promising new avenues for immunotherapy.

Getting Therapeutic Sound Waves Through Thick Skulls

August 2, 2017

…of neurological diseases and cancers, but getting therapeutic sound waves through the skull and into the brain is no easy task. To address this problem, an international team of researchers has developed a window-like cranial implant through which doctors can deliver ultrasound treatments on demand and on a recurring basis…

Drug Targets Hard-to-Reach Leukemia Stem Cells Responsible for Relapses

January 17, 2013

Researchers at the University of California, San Diego School of Medicine have discovered that hard-to-reach, drug-resistant leukemia stem cells (LSCs) that overexpress multiple pro-survival protein forms are sensitive – and thus vulnerable – to a novel cancer stem cell-targeting drug currently under development.

Old Drugs Find New Target For Treating Brain Tumor

November 18, 2011

…Diego School of Medicine and UC San Diego Moores Cancer Center, in collaboration with colleagues in Boston and South Korea, say they have identified a novel gene mutation that causes at least one form of glioblastoma (GBM), the most common type of malignant brain tumor.

Gene Editing Technique Helps Find Cancer’s Weak Spots

March 20, 2017

Genetic mutations that cause cancer also weaken cancer cells, allowing researchers to develop drugs that will selectively kill them. This is called “synthetic lethality” because the drug is only lethal to mutated (synthetic) cells. Researchers at UC San Diego School of Medicine and Jacobs School of Engineering developed a method…

Precision Oncology via Artificial Intelligence on Cancer Biopsies

July 31, 2024

An artificial intelligence method to detect biomarkers in tumor biopsies promises to cut weeks and thousands of dollars from cancer detection, extending the benefits of precision oncology to underserved and under-resourced patients.

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