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Your search for “Cancer Research” returned 1389 results

Researchers Discover Specific Tumor Environment That Triggers Cells to Metastasize

November 21, 2017

…environment surrounding a tumor can trigger metastatic behavior in cancer cells. Specifically, when tumor cells are confined in a dense environment, the researchers found that they turn on a specific set of genes and begin to form structures that resemble blood vessels.

Cancer and the Goldilocks Effect

April 3, 2014

Researchers at the University of California, San Diego School of Medicine have found that too little or too much of an enzyme called SRPK1 promotes cancer by disrupting a regulatory event critical for many fundamental cellular processes, including proliferation.

Novel Imaging Model Helps Reveal New Therapeutic Target for Pancreatic Cancer

June 6, 2016

…most common of pancreatic cancers, is extraordinarily lethal, with a 5-year survival rate of just 6 percent. In a new study, researchers at University of California San Diego School of Medicine and Moores Cancer Center, together with colleagues at Keio University, the University of Nebraska and Ionis Pharmaceuticals describe an…

UCSD-based Cancer Consortium Receives 5-Year, $20 Million Grant Renewal

September 27, 2012

…grant by the National Cancer Institute, part of the National Institutes of Health. The grant is the second renewal of funding for a broad-based effort designed to better understand the pathology of CLL – the most common form of leukemia in the Western world – and develop new drugs and…

Non-Coding DNA Located Outside Chromosomes May Help Drive Glioblastoma

November 21, 2019

According to a new Cell study, extra DNA scooped up and copied alongside cancer-causing genes helps keep tumors going — elements that could represent new drug targets for brain tumors and other cancers notoriously difficult to treat.

Omega Factor: Novel Method Measures Mortality Risk When Multiple Diseases Threaten

April 11, 2016

Researchers at the University of California, San Diego School of Medicine have developed a novel method for assessing mortality risk in elderly patients with cancer who also suffer from other serious diseases or conditions. The prognostic model, they say, is more precise and provides a more useful tool for determining…

Women Needed to Contribute to WISDOM for Breast Cancer Screening

November 6, 2017

…medical centers, including Moores Cancer Center at UC San Diego Health, have joined together to recruit 100,000 women in California to be part of WISDOM: a clinical trial to uncover whether annual mammograms are the best way to screen for breast cancer, or whether a more personalized approach could deliver…

Novel Therapeutic Agent for Pediatric Cancer Developed at UC San Diego in Clinical Trials

August 11, 2015

…Durden, MD, PhD, pediatric researcher at University of California, San Diego School of Medicine and Moores Cancer Center has identified and developed a novel therapeutic target for neuroblastoma, the second most common solid-tumor childhood cancer. The agent, named SF1126, acts by inhibiting the part of the cancer cell engine that…

How Loss of Single Gene Fuels Deadly Childhood Brain Cancer

September 10, 2020

UC San Diego researchers describe how the functional loss of a single gene negatively impacts neural development and promotes the growth of a particularly deadly form of pediatric brain cancer.

UC San Diego Cancer Scientists Identify New Drug Target for Multiple Tumor Types

July 11, 2019

A dysfunctional enzyme involved in building cancer cell membranes helps fuel tumor growth; when it’s disabled or depleted in mouse models, tumors shrank significantly.

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