April 18, 2016
Cancer is rarely the result of a single mutation in a single gene. Rather, tumors arise from the complex interplay between any number of mutually exclusive abnormal changes in the genome, the combinations of which can be unique to each individual patient. To better characterize the functional context of genomic…
September 26, 2022
Sociology professor Michel Estefan redefines classroom culture.
September 29, 2022
An international team of scientists, co-led by researchers at the University of California San Diego School of Medicine, has created the first pan-cancer mycobiome atlas—a survey of 35 types of cancer and their associated fungi.
July 3, 2012
Research suggests that patients with leukemia sometimes relapse because standard chemotherapy fails to kill the self-renewing leukemia initiating cells, often referred to as cancer stem cells. In such cancers, the cells lie dormant for a time, only to later begin cloning, resulting in a return and metastasis of the disease.…
December 13, 2016
Researchers at University of California San Diego School of Medicine have discovered that lack of two types of enzymes can lead to liver disease and cancer in mice. In human liver tumors, they found that deficiencies in these two enzymes, Shp2 and Pten, are associated with poor prognosis. The study,…
May 19, 2016
Researchers at University of California San Diego School of Medicine and Sanford Burnham Prebys Medical Discovery Institute have discovered that high levels of the protein p62 in human liver samples are strongly associated with cancer recurrence and reduced patient survival. In mice, they also found that p62 is required for…
November 14, 2022
Joseph A. Califano III, MD, has been named director of Moores Cancer Center at UC San Diego Health.
November 3, 2015
Researchers at the University of California, San Diego are seeking residents of San Diego County for a study on how the places in which we spend our time (home, work, neighborhoods) affect cancer risk factors. The aim of the “Community of Mine” study is to determine if there is a…
January 6, 2021
Biologists have unraveled the mystery of how chromosomes are inherited correctly every time a cell divides. They discovered how a “matchmaker” molecule stops cell division until components are ready to be split. Alterations in the process can result in birth defects and certain cancers.
July 29, 2015
A new study by researchers at University of California, San Diego School of Medicine reveals a protein’s critical – and previously unknown – role in the development and progression of acute myeloid leukemia (AML), a fast-growing and extremely difficult-to-treat blood cancer. The finding offers a novel target for better treating…
