June 10, 2015
…antibiotic azithromycin kills many multidrug-resistant bacteria very effectively — when tested under conditions that closely resemble the human body and its natural antimicrobial factors. The researchers believe the finding, published June 10 by EBioMedicine, could prompt an immediate review of the current standard of care for patients with certain so-called…
January 26, 2016
Researchers at the University of California, San Diego School of Medicine and Veterans Affairs San Diego Healthcare System report data suggesting that e-cigarettes are toxic to human airway cells, suppress immune defenses and alter inflammation, while at the same time boosting bacterial virulence. The mouse study is published January 25…
January 22, 2016
…an advance that could slow the appearance of drug resistance and allow doctors to more rapidly identify the appropriate treatment for patients with life threatening bacterial infections.
May 24, 2012
Antimicrobial peptides (AMPs) are molecules produced in the skin to fend off infection-causing microbes. Vitamin D has been credited with a role in their production and in the body’s overall immune response, but scientists at the University of California, San Diego School of Medicine say a hormone previously associated only…
October 19, 2021
Researchers at UC San Diego School of Medicine identify a strain of bacteria on healthy cats that produces antibiotics against severe skin infections. The findings may soon lead to new bacteriotherapies for humans and their pets, wherein cat bacteria is applied via topical cream or spray.
December 16, 2019
Scientists have developed a CRISPR-based gene-drive system that inactivates a gene rendering bacteria antibiotic-resistant. The new system leverages technology developed by UC San Diego biologists in insects and mammals that biases genetic inheritance of preferred traits called “active genetics.”
September 3, 2019
CARB-X, an international funder of efforts to fight antimicrobial resistance, is awarding up to $15 million to develop a strep throat vaccine based on original research at UC San Diego.
January 3, 2022
Researchers have shown that highly accurate, long-read genomic sequencing technology (HiFi), combined with advanced algorithms, can differentiate between nearly identical organisms, allowing researchers to more completely catalogue microbial communities.
April 27, 2022
Researchers at UC San Diego have used a systems biology approach to parse the genetic diversity of Clostridioides difficile, a particularly problematic pathogen, particularly in health care settings.
July 7, 2022
UC San Diego researchers say they may have found the reason why multiple human clinical trials of staphylococcus vaccines have failed: the bacteria knows us too well.
