October 7, 2013
By tinkering with their chemical structures, researchers at the University of California, San Diego School of Medicine have essentially re-invented a class of popular antimicrobial drugs, restoring and in some cases, expanding or improving, their effectiveness against drug-resistant pathogens in animal models.
February 22, 2017
…determine how many had antimicrobial properties and at what rate these are found on healthy and non-healthy skin. In a paper published in Science Translation Medicine, the team reports isolating and growing good bacteria that produce antimicrobial peptides and successfully transplanting it to treat patients with the most common type…
January 5, 2015
When it comes to skin infections, a healthy and robust immune response may depend greatly upon what lies beneath. In a new paper published in the January 2, 2015 issue of Science, researchers at the University of California, San Diego School of Medicine report the surprising discovery that fat cells…
October 14, 2015
…strep virulence — the protein’s ability to hold off antimicrobial peptides. The study is published October 14 by Cell Host & Microbe.
January 22, 2018
In a paper published in Nature Microbiology on Jan. 22, a team of American and Russian computer scientists described a new algorithm that identified an order of magnitude, or roughly 10 times more, naturally occurring antibiotics all previous studies.
October 18, 2022
Victor Nizet, MD, Distinguished Professor of Pediatrics at University of California San Diego School of Medicine and Pharmacy at Skaggs School of Pharmacy and Pharmaceutical Sciences, has been elected to the National Academy of Medicine.
May 26, 2016
…such as Pseudomonas and methicillin-resistant Staphylococcus aureus. First, though, they had to wait until Janie turned 14 before she was legally allowed to work in the lab. “I was amazed at how Janie approached the science, even at such a young age,” Nizet said. “Her questions, independent thinking, and troubleshooting…
April 2, 2015
Methicillin-resistant Staphylococcus aureus (MRSA), an antibiotic-resistant superbug, can cause life-threatening skin, bloodstream and surgical site infections or pneumonia. Researchers at the University of California, San Diego School of Medicine now report that cigarette smoke may make matters worse. The study, published March 30 by Infection and Immunity, shows that MRSA…
May 30, 2018
…between new antibiotics and drug-resistant bacteria—and scientists are challenged to keep up. By 2050, according to a Wellcome Trust study, deaths from deadly infections will be more common than cancer deaths. Scientists report that currently antimicrobial resistance causes 23,000 deaths annually in the U.S.; 700,000 deaths worldwide. Better methods to…
December 8, 2015
Biologists at UC San Diego have found that a method they developed to identify and characterize new antibiotics can be employed to screen natural products quickly for compounds capable of controlling antibiotic resistant bacteria.
