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Your search for “Organoids” returned 69 results

Machine Learning Algorithm Can’t Distinguish These Lab Mini-Brains from Preemie Babies

August 29, 2019

Nine-month-old brains-in-a-dish and the brains of premature newborn babies generate similar electrical patterns, as captured by electroencephalogram (EEG) — the first time such brain activity has been achieved in a cell-based laboratory model.

Lab-Grown Human Brain Organoids Mimic an Autism Spectrum Disorder, Help Test Treatments

December 8, 2020

UC San Diego researchers used brain organoids to identify two drug candidates that counteract the genetic deficiencies that cause Rett syndrome, a rare form of autism spectrum disorder.

Human Gut-in-a-Dish Model Helps Define ‘Leaky Gut,’ and Outline a Pathway to Treatment

February 10, 2020

UC San Diego researchers use 3D human gut organoids to reveal the molecular system that keeps intestinal linings sealed, demonstrate how the system breaks down and how it can be strengthened with the diabetes drug metformin.

UC San Diego Develops First-In-Kind Protocol for Creating ‘Wired Miniature Brains’

June 10, 2024

Researchers have developed — and shared — a process for creating brain cortical organoids — essentially miniature artificial brains with functioning neural networks

How a Single Gene Alteration May Have Separated Modern Humans from Predecessors

February 11, 2021

UC San Diego researchers discovered a single gene alteration that may help explain cognitive differences between modern humans and our predecessor, and used that information to develop Neanderthal-like brain organoids in the lab.

Organoids Derived From Gut Stem Cells Reveal Two Distinct Molecular Subtypes of Crohn’s Disease

September 26, 2024

UC San Diego researchers discover two distinct molecular subtypes of Crohn’s disease using patient-derived organoids, opening the door to personalized treatment for the chronic inflammatory bowel disease.

UC San Diego First to Test Cancer Drugs in Space Using Private Astronaut Mission

May 22, 2023

The latest space experiments from UC San Diego and Axiom Space will explore therapies for breast and colorectal cancer aboard the ISS, and monitor astronauts’ stem cell health over time.

$12.7M Grant to Establish New Center to Investigate Genetic Basis of Autism and Schizophrenia

October 10, 2024

Funded by a California Institute for Regenerative Medicine grant, researchers in the UC San Diego Verge Center aim to uncover the genetic mechanisms behind neuropsychiatric disorders.

UC San Diego Receives $1.3M from W. M. Keck Foundation to Study Origins of Dementia

August 16, 2022

Researchers at the University of California San Diego have received a $1.3 million grant from the W.M. Keck Foundation for a project that could help scientists better understand the role misfolded tau proteins play in causing neurodegenerative diseases like dementia, which may lead to more effective

Brazilian Zika Virus Strain Causes Birth Defects in Experimental Models

May 11, 2016

Researchers at University of California San Diego School of Medicine, with colleagues in Brazil and Senegal, have described the first “direct experimental proof” that the Brazilian strain of Zika virus can actually cause severe birth defects. The findings are published in the May 11 online issue of Nature.

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