February 11, 2016
February 11, 2016 —
Clear images of minute packages meant to shield healthy cells from potent anti-cancer drugs have helped researchers evaluate a promising of new approach to chemotherapy.
June 13, 2018
June 13, 2018 —
…billion people globally, yet are rarely the target of new drug discovery efforts. Leveraging its strengths in molecular biology, clinical research and pharmaceutical sciences, the University of California San Diego has now launched a new Center for Anti-Parasitic Drug Discovery and Development to address this unmet need in global health.
July 27, 2015
July 27, 2015 —
Researchers at University of California, San Diego School of Medicine have established the safety and dosing of a new drug for treating blood cancers. The findings are published online July 27 in The Lancet Haematology.
May 11, 2016
May 11, 2016 —
Drug-related overdoses are the leading cause of injury-related deaths in the United States, surpassing motor vehicle accidents at 44,000 fatalities annually. In response, researchers at University of California San Diego School of Medicine have partnered with the San Diego County Sheriff’s Department to implement and study a program that requires…
June 21, 2012
June 21, 2012 —
…Medicine have uncovered a new signal transduction pathway specifically devoted to the regulation of alternative RNA splicing, a process that allows a single gene to produce or code multiple types of protein variants. The discovery, published in the June 27, 2012 issue of Molecular Cell, suggests the new pathway might…
September 25, 2012
September 25, 2012 —
Researchers at University of California, San Diego Moores Cancer Center are evaluating the safety and tolerability of a synthetic cannabinoid called dexanabinol (ETS2101). Delivered as a weekly intravenous infusion, the drug is being tested in patients with all forms of brain cancer, both primary and metastatic.
October 7, 2013
October 7, 2013 —
By tinkering with their chemical structures, researchers at the University of California, San Diego School of Medicine have essentially re-invented a class of popular antimicrobial drugs, restoring and in some cases, expanding or improving, their effectiveness against drug-resistant pathogens in animal models.
May 21, 2012
May 21, 2012 —
…of Medicine has led to identification of an existing drug that is effective against Entamoeba histolytica. This parasite causes amebic dysentery and liver abscesses and results in the death of more than 70,000 people worldwide each year.
February 8, 2016
February 8, 2016 —
…mimics the human liver’s sophisticated structure and function. The new model could be used for patient-specific drug screening and disease modeling. Researchers said the advance could help pharmaceutical companies save time and money when developing new drugs.
February 1, 2024
February 1, 2024 —
UC San Diego scientists are working to flip the script on drug addiction with a $1.3 million grant from the W.M. Keck Foundation. Their new approach, called negative feedback chemogenetics, works by leveraging the body’s biochemical feedback processes to disrupt pathways associated with addiction.