July 13, 2015
From the smell of flowers to the taste of wine, our perception is strongly influenced by prior knowledge and expectations, a cognitive process known as top-down control. In a University of California, San Diego School of Medicine study, a research team led by Takaki Komiyama, PhD, assistant professor of neurosciences…
September 6, 2016
A team of researchers has built a mathematical model that describes the molecular events associated with the beginning stage of learning and memory formation in the human brain. The research paves the way for understanding cognitive function and neurodegenerative diseases—at the molecular and cellular levels.
January 17, 2018
Confirming earlier computational models, researchers at University of California San Diego and UC San Diego School of Medicine, with colleagues in Arizona and Louisiana, report that episodic memories are encoded in the hippocampus of the human brain by distinct, sparse sets of neurons.
November 9, 2011
In a paper published in the November 9 issue of The Journal of Neuroscience, researchers at the University of California, San Diego School of Medicine and University of Washington describe in deeper detail the pathology of a devastating neurological disorder, but also reveal new cellular targets for possibly slowing its…
March 16, 2023
UC San Diego researchers use a DNA designer drug to restore key protein levels in motor neurons, delaying paralysis in a mouse model of ALS.
September 29, 2017
Researchers at University of California San Diego School of Medicine have developed the first mice that lack the Upf3b gene, providing a new model for studying its underlying role in intellectual disabilities and neurodevelopmental disorders.
September 4, 2013
Biologists at the University of California, San Diego have identified a new component of the cellular mechanism by which humans and animals automatically check the quality of their nerve cells to assure they’re working properly during development.
November 8, 2024
Researchers at UC San Diego identify a key pathway leading to neurodegeneration in early stages of ALS, hinting at the potential for short-circuiting the progression of the fatal disease if diagnosed early.
October 20, 2016
Although only 10 percent of amyotrophic lateral sclerosis (ALS) cases are hereditary, a significant number of them are caused by mutations that affect proteins that bind RNA, a type of genetic material. University of California San Diego School of Medicine researchers studied several ALS cases with a mutation in a…
April 30, 2015
…of injury to a neuron’s communication wire in the spinal cord — the axon — determines whether the neuron simply stabilizes or attempts to regenerate. The study, published April 30 by Neuron, demonstrates how advances in live-imaging techniques are revealing new insights into the body’s ability to respond to spinal…
