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Your search for “Neurology” returned 420 results

How Loss of Single Gene Fuels Deadly Childhood Brain Cancer

September 10, 2020

UC San Diego researchers describe how the functional loss of a single gene negatively impacts neural development and promotes the growth of a particularly deadly form of pediatric brain cancer.

New Grant Seeks to Fill Knowledge Gaps Regarding Spina Bifida

November 20, 2020

Researchers at UC San Diego School of Medicine and Rady Children’s Institute for Genomic Medicine have been awarded a five-year, $8.3 million grant from the National Institutes of Health to investigate the causes of spina bifida, the most common structural defect of the central nervous system.

Lab-Grown Human Brain Organoids Mimic an Autism Spectrum Disorder, Help Test Treatments

December 8, 2020

UC San Diego researchers used brain organoids to identify two drug candidates that counteract the genetic deficiencies that cause Rett syndrome, a rare form of autism spectrum disorder.

How a Single Gene Alteration May Have Separated Modern Humans from Predecessors

February 11, 2021

UC San Diego researchers discovered a single gene alteration that may help explain cognitive differences between modern humans and our predecessor, and used that information to develop Neanderthal-like brain organoids in the lab.

First-in-Human Clinical Trial to Assess Gene Therapy for Alzheimer’s Disease

February 18, 2021

UC San Diego researchers have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer’s disease or Mild Cognitive Impairment, a condition that often precedes full-blown dementia.

Human Lung and Brain Organoids Respond Differently to SARS-CoV-2 Infection in Lab Tests

February 24, 2021

UC San Diego School of Medicine researchers are using stem cell-derived organoids to study how SARS-CoV-2 interacts with various organ systems. Their findings may help explain the wide variety in COVID-19 symptoms and aid the search for therapies.

Autism Center at UC San Diego Receives $1.5 Million Gift

April 14, 2021

The UC San Diego Autism Center for Excellence has received a $1.5 million gift from Kristin Farmer, founder and chief executive officer of ACES, a company that provides services to children with autism and their families, to support the work of Karen Pierce, co-director of the Autism Center.

Neural Implant Monitors Multiple Brain Areas at Once, Provides New Neuroscience Insights

April 27, 2021

How do different parts of the brain communicate with each other during learning and memory formation? A study by researchers at UC San Diego takes a first step at answering this fundamental neuroscience question, thanks to a neural implant that monitors multiple brain regions at the same time.

Controlling Cholesterol in Microglia Alleviates Chronic Pain, Opioid-Free

May 10, 2021

Using a mouse model, researchers discover pivotal role of cholesterol in chronic pain often caused by chemotherapy, and propose novel therapy.

Research Uncovers How ‘Non-professional’ Cells Can Trigger Immune Response

May 26, 2021

Researchers are finding new details on the complex dynamics involved in how organisms sense an infection from pathogens. The researchers found that worms can sense changes in their metabolism in order to unleash protective defenses, even if they don’t directly sense an incursion from pathogens.

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