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Your search for “NAFLD” returned 42 results

Liver Fibrosis ‘Off Switch’ Discovered in Mice

January 23, 2020

UC San Diego School of Medicine researchers identified several genetic switches, or transcription factors, that determine whether or not liver cells produce collagen — providing a new therapeutic target for liver fibrosis.

UC San Diego Partners with Janssen to Research New Approaches to Treat Metabolic Diseases

June 15, 2017

University of California San Diego School of Medicine has entered a five-year strategic partnership with Janssen Pharmaceuticals, Inc., part of the Janssen Pharmaceutical Companies of Johnson & Johnson, to discover meaningful treatments for metabolic diseases.

New Mouse Model Points to Therapy for Liver Disease

August 18, 2014

In a paper published online in Cancer Cell, scientists at the University of California, San Diego School of Medicine describe a novel mouse model that closely resembles human NASH and use it to demonstrate that interference with a key inflammatory protein inhibits both the development of NASH and its progression…

Common Acid Reflux Medications Promote Chronic Liver Disease

October 10, 2017

Approximately 10 percent of Americans take a proton pump inhibitor drug to relieve symptoms of frequent heartburn and acid reflux. That percentage can be much higher for people with chronic liver disease. Researchers at University of California San Diego School of Medicine have discovered evidence in mice and humans that…

Causes of Liver Cancer are Changing Around the World: Some Up, Some Down

June 6, 2022

UC San Diego researchers report that the causes and death rates of liver cancer are changing around the world.

Bioengineers Receive $12M Grant from NIH to Further Research on Building Blocks of Human Metabolism

August 20, 2018

The University of California San Diego has received a $12 million, four-year grant from the National Institutes of Health to expand the Metabolomics Workbench, a searchable, interactive repository of data for all research in the field of metabolomics—the study of the small molecules called metabolites that are found within cells…

Study: Two Enzymes Control Liver Damage in NASH

February 6, 2020

After identifying a molecular pathway that allows nonalcoholic steatohepatitis (NASH) to progress into liver cell death, University of California San Diego School of Medicine researchers were able to use these pathways to halt further liver damage.

Clinical Trial to Investigate whether Hypertension Drug Ameliorates COVID-19 Severity

April 30, 2020

UC San Diego scientists have launched a clinical trial to investigate whether a drug approved for treating high blood pressure might also reduce the severity of COVID-19 infections, lowering rates for intensive care unit admissions, the use of mechanical ventilators and all-cause mortality.

How Chronic Inflammation Tips the Balance of Immune Cells to Promote Liver Cancer

November 8, 2017

Chronic inflammation is known to drive many cancers, especially liver cancer. Researchers have long thought that’s because inflammation directly affects cancer cells, stimulating their division and protecting them from cell death. But University of California San Diego School of Medicine researchers have now found that chronic liver inflammation also promotes…

UC San Diego Health Ranked #1 by U.S. News & World Report

July 27, 2020

UC San Diego Health is ranked first in San Diego and sixth in California, placing it among the nation’s best hospitals, according to the 2020-2021 U.S. News & World Report. Eight common procedures and conditions were also rated “high performing.”

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