A gene therapy for chronic pain could offer a safer, non-addictive alternative to opioids. By temporarily repressing a gene involved in sensing pain, the treatment increased pain tolerance in mice, lowered their sensitivity to pain and provided months of pain relief without causing numbness.
Bioengineers at UC San Diego and San Diego State University have discovered a key feature that allows cancer cells to break from typical cell behavior and migrate away from stiffer tissue in a tumor, shedding light on the process of metastasis and offering possible new targets for cancer therapies.
This shirt harvests and stores energy from the human body to power small electronics. UC San Diego nanoengineers call it a "wearable microgrid"—it combines energy from the wearer's sweat and movement to provide renewable power for wearable devices.
Researchers at University of California San Diego School of Medicine and Moores Cancer Center demonstrated that a new tumor-penetrating therapy could enhance the effects of chemotherapy, reduce the spread of pancreatic cancer and increase survival in animal models.
A coordinated conservation effort that removed rats from Hawadax Island, formerly known as “Rat Island,” has become a new example of how ecosystems can fully recover to their natural state in little more than a decade. The results are described in a report led by a UC San Diego scientist.
New research published in two papers by UC San Diego scientists describes novel achievements designed to make the implementation of gene drives safer and more controllable. The new split drive and home-and-rescue systems address concerns about the release of gene drives in wild populations.
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