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Engineered Bone Marrow Could Make Transplants Safer

Engineers at the University of California San Diego have developed biomimetic bone tissues that could one day provide new bone marrow for patients needing transplants.

Scientists Complete First EPA-Approved Outdoor Field Trial for Genetically Engineered Algae

Scientists have successfully completed the first outdoor field trial sanctioned by the EPA for genetically engineered algae. Algae tested under real-world conditions in outdoor ponds demonstrated that genetically engineered strains can be successfully cultivated outdoors without adversely impacting native algae populations.

Talking Science

UC San Diego’s Divisions of Biological and Physical Sciences will launch a Research Communications program designed to address that need. Funded by a two-year, $225,000 grant from the Gordon and Betty Moore Foundation, the new effort seeks to improve the ability of faculty members, postdoctoral fellows and other researchers on campus to communicate their work to the public.

First Large-Scale Population Analysis Reinforces Ketamine’s Reputation as Antidepressant

Researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego mined the FDA Adverse Effect Reporting System (FAERS) database for depression symptoms in patients taking ketamine for pain. They found that depression was reported half as often among the more than 41,000 patients who took ketamine, as compared to patients who took any other drug or drug combination for pain.

UC San Diego School of Medicine’s Christopher Glass Joins National Academy of Sciences

The U.S. National Academy of Sciences announced today the membership election of Christopher K. Glass, MD, PhD, professor in the Departments of Medicine and Cellular and Molecular Medicine at University of California San Diego School of Medicine.

Pathways Leading to Beta Cell Division Identified, May Aid Diabetes Treatment

Pancreatic beta cells help maintain normal blood glucose levels by producing the hormone insulin — the master regulator of energy (glucose). Impairment and the loss of beta cells interrupts insulin production, leading to type 1 and 2 diabetes. Using single-cell RNA sequencing, researchers at University of California San Diego School of Medicine have, for the first time, mapped out pathways that regulate beta cell growth that could be exploited to trick them to regenerate.