High Vinculin Levels Help Keep Aging Fruit Fly Hearts Young
A new discovery in how heart muscles maintain their shape in fruit flies sheds light on the crucial relationship between cardiac function, metabolism, and longevity. Researchers from the University of California San Diego discovered that maintaining high levels of the protein vinculin—which sticks heart muscle cells to one another—confers health benefits to fruit flies. Their work shows that fruit flies bred to produce 50 percent more vinculin enjoyed better cardiovascular health and lived a third of their average life span longer.