Employing CRISPR/Cas9 advancements, UC San Diego researchers are using new active genetics technology to reveal new fundamental mechanisms that control gene activity. The authors also provide experimental validation for using active genetics as an efficient means for targeted gene insertion, or “transgenesis,” and single-step replacement of genetic control elements.
In approximately 15 percent of cases where couples are unable to conceive, the underlying cause of infertility is not known. Researchers at University of California San Diego School of Medicine and in the Division of Biological Sciences at UC San Diego have identified a protein in mice that must be present in eggs for them to complete normal development. Without the protein, called ZFP36L2, the eggs appear ordinary, but they cannot be fertilized by sperm.
Three years ago, the campus launched a pilot program to promote interdisciplinary research among undergraduate and graduate students and postdoctoral fellows. The idea was to partner them with faculty mentors from at least two disciplines and provide them with funds so they could conduct research with the potential to make a real impact on society.
Sea urchin is a delicacy in Asia, South America, Europe, and increasingly in California, where the uniquely flavored roe, or uni, is used in sushi, gourmet cuisine, and products such as sauces and flavorings. But the large red sea urchin (Mesocentrotus franciscanus) caught off the coast of Southern California—the primary urchin fishery in the U.S.—is vulnerable to increased water temperatures and ocean acidification.
Two multimedia installations by Music graduate students based on the sonification of endangered coral reefs will premiere Feb. 8 as part of the 2017-2018 performance season at UC San Diego's Initiative for Digital Exploration of Arts & Sciences (IDEAS) in the Qualcomm Institute.
UC San Diego is launching an online series of eight courses in Algorithms and Data Structures on the edX platform to help students worldwide master algorithmic programming techniques to qualify for a top senior engineering job.
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